TCA Deblock
ALDRICH/L020000
Product Type: Chemical
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| bp | 39.8—40.0 °C/1,013 hPa |
| color | clear |
| clear | |
| concentration | 28-32 g/L (TCA content, titration) |
| form | liquid |
| impurities | ≤200 ppm water content (Karl Fischer) |
| product line | Proligo Reagents |
| Quality Level | 200  |
| storage condition | dry at room temperature |
| storage temp. | room temp |
| technique(s) | DNA synthesis: suitable |
| type | for DNA synthesis |
| Other Notes: | Deblock solution containing trichloroacetic acid (TCA) in dichloromethane removes the dimethoxytrityl (DMT) protecting group from the 5′hydroxyl moiety of nucleotides already incorporated into the growing nucleic acid, prior to the addition of the next phosphoramidite. Removal of the DMT allows the unprotected 5′hydroxyl moiety to react with a new phosphoramidite in a subsequent extension reaction. |
| Packaging: | 4×4 L in glass bottle |
| Packaging: | 450 mL in glass bottle |
| Preparation Note: | Trichloroacetic acid / Dichloromethane 3/100 (v/v) |
| Symbol |     GHS05,GHS07,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H315 - H318 - H335 - H336 - H351 - H410 |
| Precautionary statements | P201 - P273 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313 |
| Hazard Codes | Xn,N |
| Risk Statements | 36/37/38-40-50/53 |
| Safety Statements | 26-36/37-61 |
| RIDADR | UN2922 - class 8 - PG 3 - EHS - acidic - Corrosive liquids, toxi |
| WGK Germany | WGK 2 |
| Flash Point(F) | 212.0 °F - closed cup |
| Flash Point(C) | 100 °C - closed cup |
| bp | 39.8—40.0 °C/1,013 hPa |
| Storage Temp. | room temp |
| UNSPSC | 41116004 |