TCA Deblock
ALDRICH/L020200
Product Type: Chemical
| color | clear |
| clear Appearance of Solution | |
| concentration | 28-32 g/L (TCA Content, titration) |
| impurities | ≤200 ppm water content (Karl Fischer) |
| packaging | pkg of 4 × 2 L L020200-04 |
| product line | Proligo Reagents |
| type | for DNA synthesis |
| Other Notes: | Deblock solution containing trichloroacetic acid (TCA) in dichloromethane removes the dimethoxytrityl (DMT) protecting group from the 5′hydroxyl moiety of nucleotides already incorporated into the growing nucleic acid, prior to the addition of the next phosphoramidite. Removal of the DMT allows the unprotected 5′hydroxyl moiety to react with a new phosphoramidite in a subsequent extension reaction. |
| Packaging: | 1 pkg in glass bottle |
| Preparation Note: | Trichloroacetic acid / Dichloromethane 3/100 (v/v) |
| Symbol |     GHS05,GHS07,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H315 - H318 - H335 - H336 - H351 - H410 |
| Precautionary statements | P201 - P273 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313 |
| Hazard Codes | Xn,N |
| Risk Statements | 36/37/38-40-50/53 |
| Safety Statements | 26-36/37-61 |
| RIDADR | UN2922 - class 8 - PG 3 - EHS - acidic - Corrosive liquids, toxi |
| WGK Germany | WGK 2 |
| Flash Point(F) | 212.0 °F - closed cup |
| Flash Point(C) | 100 °C - closed cup |
| UNSPSC | 12352200 |