DCA Deblock
ALDRICH/L023050 - configured for ÄKTA® and OligoPilot®, with Toluene
Product Type: Chemical
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| color | clear |
| compatibility | configured for ÄKTA® and OligoPilot® |
| concentration | 42.2-51.6 g/L (DCA content, titration) |
| impurities | ≤200 ppm water content (Karl Fischer) |
| product line | Proligo Reagents |
| Quality Level | 200  |
| storage condition | dry at room temperature |
| type | for DNA synthesis |
| Legal Information: | ÄKTA is a registered trademark of Cytiva |
| Legal Information: | OligoPilot is a registered trademark of Cytiva |
| Other Notes: | Deblock solution containing dichloroacetic acid (DCA) in toluene removes the dimethoxytrityl (DMT) protecting group from the 5′hydroxyl moiety of nucleotides already incorporated into the growing nucleic acid, prior to the addition of the next phosphoramidite. Removal of the DMT allows the unprotected 5′hydroxyl moiety to react with a new phosphoramidite in a subsequent extension reaction. |
| Preparation Note: | Toluene / Dichloroacetic acid 97/3 (v/v) |
| Symbol |      GHS02,GHS05,GHS07,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H225 - H304 - H315 - H318 - H336 - H351 - H360FD - H373 - H410 |
| Precautionary statements | P210 - P273 - P280 - P301 + P310 - P305 + P351 + P338 - P331 |
| Hazard Codes | F,Xn,N |
| Risk Statements | 63-11-36/38-48/20-50-65-67 |
| Safety Statements | 16-26-36/37-61-62 |
| RIDADR | UN2924 - class 3 - PG 2 - EHS - acidic - Flammable liquids, corr |
| WGK Germany | WGK 2 |
| Flash Point(F) | 39.2 °F |
| Flash Point(C) | 4.0 °C |
| UNSPSC | 41116105 |