ETT Activator
ALDRICH/L030004 - 0.25M
Synonym: 5-(Ethylthio)-1H-tetrazole; 5-
MDL Number: MFCD00068733
Product Type: Custom product
| concentration | 32-35 g/L (titration) |
| form | liquid |
| impurities | ≤30 ppm water content (Karl Fischer) |
| InChI | 1S/C3H6N4S/c1-2-8-3-4-6-7 |
| InChI key | GONFBOIJNUKKST-UHFFFAOYSA |
| product line | Proligo Reagents |
| SMILES string | CCSc1nnn[nH]1 |
| type | for DNA synthesis |
| Other Notes: | Activator solution, containing 5-(Ethylthio)-1H- tetrazole (ETT) in acetonitrile, are mixed with solutions of phosphoramidites during the extension step. The activator reacts with the amidite group to form a highly reactive intermediate. The intermediate then forms an internucleotide bond with the detritylated 5′hydroxyl group of the growing oligonucleotide chain. |
| Preparation Note: | Acetonitrile / 5-(Ethylthio)-1H-Tetrazol |
| Symbol |   GHS02,GHS07 |
| Signal word | Danger |
| Hazard statements | H225 - H302 + H312 + H332 - H319 |
| Precautionary statements | P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338 |
| Hazard Codes | F,Xn |
| Risk Statements | 11-20/21/22-36 |
| Safety Statements | 16-26-36/37 |
| RIDADR | UN 1993BE 3 / PGII |
| WGK Germany | WGK 3 |
| Flash Point(F) | 35.6 °F - closed cup |
| Flash Point(C) | 2.0 °C - closed cup |
| UNSPSC | 41116105 |