ETT Activator
ALDRICH/L030080 - 0.25 M, configured for PerkinElmer, configured for Polygen, configured for MerMade, configured for ABI 3900
Synonym: 5-(Ethylthio)-1H-tetrazole; 5-
MDL Number: MFCD00068733
Product Type: Chemical
color | clear |
compatibility | configured for ABI 3900 |
configured for MerMade | |
configured for PerkinElmer | |
configured for Polygen | |
concentration | 32-35 g/L (ETT content, titration) |
form | liquid |
impurities | ≤30 ppm water content (Karl Fischer) |
InChI | 1S/C3H6N4S/c1-2-8-3-4-6-7 |
InChI key | GONFBOIJNUKKST-UHFFFAOYSA |
product line | Proligo Reagents |
SMILES string | CCSc1nnn[nH]1 |
storage condition | dry at room temperature |
type | for DNA synthesis |
Other Notes: | Activator solution, containing 5-(Ethylthio)-1H- tetrazole (ETT) in acetonitrile, are mixed with solutions of phosphoramidites during the extension step. The activator reacts with the amidite group to form a highly reactive intermediate. The intermediate then forms an internucleotide bond with the detritylated 5′hydroxyl group of the growing oligonucleotide chain. |
Preparation Note: | Acetonitrile / 5-(Ethylthio)-1H-Tetrazol |
Symbol | GHS02,GHS07 |
Signal word | Danger |
Hazard statements | H225 - H302 + H332 - H319 |
Precautionary statements | P210 - P305 + P351 + P338 |
RIDADR | UN 1993BE 3 / PGII |
WGK Germany | WGK 3 |
Flash Point(F) | 35.6 °F - closed cup - Not |
Flash Point(C) | 2 °C - closed cup - Not app |
UNSPSC | 41116105 |