Cap A
ALDRICH/L040080 - configured for PerkinElmer, configured for Polygen
Product Type: Chemical
color | clear |
compatibility | configured for PerkinElmer |
configured for Polygen | |
concentration | 88.7-108.4 g/L (Acetic Anhydride content, titration) |
form | liquid |
product line | Proligo Reagents |
storage condition | dry at room temperature |
type | for DNA synthesis |
Biochem/physiol Actions: | Cap A solution aborts chains bearing unreacted 5′ hydroxyl groups due to failure of reaction with activated phosphoramidite (typically, 1 to 2% of growing oligonucleotide chains in each synthesis cycle). These unreacted 5′ hydroxyl groups are capped with an acetyl group and thus rendered unreactive for subsequent synthesis steps. |
General description: | Cap A solution contains acetic anhydride and tetrahydrofuran (THF). It is used after the phosphoramidite reaction/coupling step. |
Packaging: | 4×2, 4 L in glass bottle |
Packaging: | 6×200 mL in glass bottle |
Preparation Note: | Acetic Anhydride / Tetrahydrofurane 9.1/90.9 (v/v) |
Symbol | GHS02,GHS05,GHS07,GHS08 |
Signal word | Danger |
Hazard statements | H225 - H302 + H332 - H315 - H318 - H335 - H336 - H351 |
Precautionary statements | P210 - P280 - P301 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313 |
RIDADR | UN 2056 3 / PGII |
WGK Germany | WGK 1 |
Flash Point(F) | -6.2 °F - closed cup |
Flash Point(C) | -21.2 °C - closed cup |
Supplemental Hazard Statements | EUH019 - EUH071 |
UNSPSC | 12352200 |