Ethyl acetate
ALDRICH/L092004
Synonym: EtOAc
CAS Number: 141-78-6
Empirical Formula (Hill Notation): C4H8O2
Molecular Weight: 88.11
EC Number: 205-500-4
MDL Number: MFCD00009171
Linear Formula: CH3COOC2H5
Product Type: Custom product
| assay | 100% (GC) |
| autoignition temp. | 801 °F |
| bp | 76.5-77.5 °C (lit.) |
| density | 0.902 g/mL at 25 °C (lit.) |
| expl. lim. | 2.2-11.5 %, 38 °F |
| form | liquid |
| InChI | 1S/C4H8O2/c1-3-6-4(2)5/h3 |
| InChI key | XEKOWRVHYACXOJ-UHFFFAOYSA |
| mp | −84 °C (lit.) |
| Quality Level | 200  |
| refractive index | n |
| SMILES string | CCOC(C)=O |
| solubility | water: soluble |
| vapor density | 3 (20 °C, vs air) |
| vapor pressure | 73 mmHg ( 20 °C) |
| Application: | Ethyl acetate may be used in the following studies:• As a solvent for the isolation of Rose hip (Rosa canina L., Rosaceae) powder, via sonication. • As a solvent for the abstraction of volatile thiols from wine for their quantitative estimation by gas chromatography/mass spectrometry (GC-MS). • Preparation of thin films of TiO2 (titanium dioxide) on glass. • As an extraction medium in the multi-residue analysis of pesticide residues in fruit and vegetables. • Acetylaton of primary amines to form amides in the presence of dimethyltin(IV) acetic acid distannoxane. |
| General description: | In the solid-phase synthesis of oligonucleotides, liquid reagents are used in each step of the synthesis cycle. Overall synthesis performance, and therefore total product yield and purity of the crude oligonucleotide, is highly dependent on the chemical purity of the monomers and the supporting liquid reagents and other solvents like ethylacetate, dichloromethane, and dimethylformadine .Ethyl acetate (EA), a carboxylate ester, is a bio-friendly organic solvent with a wide range of industrial applications. Ethyl acetate can be obtained via an esterification reaction between ethyl alcohol and acetic acid in the presence of sulfuric acid. Its synthesis by reactive distillation and by acceptorless dehydrogenative dimerization of ethanol has been explored. Its ability as an acyl acceptor in the immobilized lipase-mediated preparation of biodiesel from crude vegetable oils has been examined. The complete degradation of ethyl acetate to CO2 using manganese octahedral molecular sieve (OMS-2) has been investigated. EA is an effective alternate solvent of diethyl ether, employed for the concentration of eggs, larvae, and cysts in fecal specimens during the Formalin-ether sedimentation technique. |
| Symbol |   GHS02,GHS07 |
| Signal word | Danger |
| Hazard statements | H225 - H319 - H336 |
| Precautionary statements | P210 - P233 - P261 - P280 - P303 + P361 + P353 - P370 + P378 |
| Hazard Codes | F,Xi |
| Risk Statements | 11-36-66-67 |
| Safety Statements | 16-26-33 |
| RIDADR | UN1173 - class 3 - PG 2 - Ethyl acetate |
| WGK Germany | WGK 1 |
| Flash Point(F) | 26.6 °F - closed cup |
| Flash Point(C) | -3.0 °C - closed cup |
| Supplemental Hazard Statements | EUH066 |
| Purity | 100% (GC) |
| bp | 76.5-77.5 °C (lit.) |
| mp | −84 °C (lit.) |
| Density | 0.902 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12352200 |