Methoxyacetyl chloride

ALDRICH/M9653 - 97%

Synonym: 2-methoxyacetyl chloride; Methoxyacetic acid chloride

CAS Number: 38870-89-2
Empirical Formula (Hill Notation): C₃H₅ClO₂
Molecular Weight: 108.52
EC Number: 254-169-2
MDL Number: MFCD00000728
Linear Formula: CH₃OCH₂COCl
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-M9653-1G	1 g	$48.20 1/EAAdd To Favorites	Add To Favorites
45-M9653-10G	10 g	$84.30 1/EAAdd To Favorites	Add To Favorites

assay	97%
bp	112-113 °C (lit.)
density	1.187 g/mL at 25 °C (lit.)
form	liquid
InChI	1S/C3H5ClO2/c1-6-2-3(4)5/h2H2,1H3
InChI key	JJKWHOSQTYYFAE-UHFFFAOYSA-N
Quality Level	100
refractive index	n20/D 1.419 (lit.)
SMILES string	COCC(Cl)=O
storage temp.	2-8°C

Application:

Methoxyacetyl chloride can be used for methoxyacetylation of:
• Bilocularin A to synthesize 8-Methoxyacetoxybilocularin A.
• Substituted and unsubstituted benzamides to synthesize N-(2-methoxyacetyl)-benzamides.

It can also be used for the synthesis of β-lactams by reacting with imines. and in the post-synthetic modification of the metal-organic framework (MOF), MIL-101, to synthesize a catalyst for cycloaddition reaction of CO₂ with propylene oxide.

Packaging:

1, 10 g in glass bottle

Symbol	GHS02,GHS05,GHS06
Signal word	Danger
Hazard statements	H226 - H314 - H331 - H335
Precautionary statements	P210 - P233 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
Hazard Codes	C
Risk Statements	10-34-36/37
Safety Statements	26-36/37/39-45
RIDADR	UN 2920 3(8) / PGII
WGK Germany	WGK 3
Flash Point(F)	82.4 °F
Flash Point(C)	28 °C

Purity	97%
bp	112-113 °C (lit.)
Density	1.187 g/mL at 25 °C (lit.)
Refractive Index	n20/D 1.419 (lit.)
Storage Temp.	2-8°C
UNSPSC	12352100