Biotin-dPEG®12-TFP ester
ALDRICH/QBD10008
Empirical Formula (Hill Notation): C43H69F4N3O16S
Molecular Weight: 992.08
Linear Formula: C43H69F4N3O16S
Product Type: Chemical
assay | >90% |
form | solid or viscous liquid |
polymer architecture | shape : linear functionality : monofunctional |
reaction suitability | reaction type: Biotinylations |
reaction type: Biotinylations reactivity: amine reactive |
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reagent type: cross-linking reagent | |
shipped in | ambient |
SMILES string | O=C(CCOCCOCCOCCOCCOCCOCCO |
storage temp. | −20°C |
Features and Benefits: | Biotin-dPEG®12-TFP ester has 2,3,5,6-tetrafluorophenyl (TFP) moiety whcih hydrolyze more slowly than NHS esters in aqueous media and is more reactive towards amines than NHS esters. The single molecular weight Biotin-dPEG®12-TFP ester has a long spacer of precise length (47.6 Å) between the biotin moiety and the labeled molecule. This dPEG spacer imparts a high degree of water solubility to the biotin label. For biotinylated peptides and proteins, the PEG spacer dramatically reduces aggregation and precipitation of the modified molecule and reduces non-specific binding of the molecule, both of which are common problems with molecules that have been biotinylated with the widely used NHS-LC-biotin. |
Legal Information: | dPEG is a registered trademark of Quanta BioDesign |
Legal Information: | Products Protected under U.S. Patents # 7,888,536 B2 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | >90% |
Storage Temp. | −20°C |
UNSPSC | 12352200 |