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NHS-dPEG®12-biotin

ALDRICH/QBD10198

Synonym: NHS-PEG Linker; Polyethylene glycol

Empirical Formula (Hill Notation): C41H72N4O18S
Molecular Weight: 941.09
Linear Formula: C41H72N4O18S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-QBD10198-50MG 50 mg
 $271.00
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45-QBD10198-1000MG 1000 mg
 $2010.00
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assay >90%
form solid or viscous liquid
InChI 1S/C41H72N4O18S/c46-36(4-2-1-3-35-40-34(33-64-35)43-41(50)44-40)42-8-10-52-12-14-54-16-18-56-20-22-58-24-26-60-28-30-62-32-31-61-29-27-59-25-23-57-21-19-55-17-15-53-13-11-51-9-7-39(49)63-45-37(47)5-6-38(45)48/h34-35,40H,1-33H2,(H,42,46)(H2,43,44,50)
InChI key WOLXSUFTTIRQOU-UHFFFAOYSA-N
polymer architecture shape : linear
functionality : monofunctional
reaction suitability reagent type: cross-linking reagent
reaction type: Biotinylations
reactivity: amine reactive
shipped in ambient
SMILES string O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCCC1C2NC(NC2CS1)=O)=O)ON3C(CCC3=O)=O
storage temp. −20°C
Features and Benefits: NHS-dPEG®12-biotin is used extensively to label molecules that contain a free amine with biotin. The single molecular weight NHS-dPEG®12-biotin has a long spacer of precise length (47.6 Å) between the biotin moiety and the labeled molecule. This dPEG® spacer imparts a high degree of water solubility to the biotin label. For biotinylated peptides and proteins, the dPEG® spacer dramatically reduces aggregation and precipitation of the modified molecule and reduces non-specific binding of the molecule, both of which are common problems with molecules that have been biotinylated with the widely used NHS-LC-biotin.
Legal Information: dPEG is a registered trademark of Quanta BioDesign
Legal Information: Products Protected under U.S. Patents # 7,888,536 B2
RIDADR NONH for all modes of transport
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity >90%
Storage Temp. −20°C
UNSPSC 12161502

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