TFP-dPEG®12-biotinidase resistant biotin
ALDRICH/QBD10204
Empirical Formula (Hill Notation): C47H76F4N4O17S
Molecular Weight: 1077.18
Linear Formula: C47H76F4N4O17S
Product Type: Chemical
assay | >90% |
form | solid or viscous liquid |
polymer architecture | shape : linear functionality : heterobifunctional |
reaction suitability | reaction type: Biotinylations reactivity: amine reactive |
reagent type: cross-linking reagent | |
shipped in | ambient |
SMILES string | O=C1NC(C2N1)CSC2CCCCC(NC( |
storage temp. | −20°C |
Features and Benefits: | TFP-dPEG®12-biotinidase resistant biotin contains an amine reactive TFP ester and chemically modified biotin that is stable in the presence of biotinidase. Resistance to biotinidase cleavage of biotin is necessary in some biotechnology applications. The chemical modification to biotin imparts resistance to biotinidase cleavage without reducing the strength of biotin-avidin binding. The single molecular weight dPEG® spacer imparts water solubility, prevents aggregation and precipitation of labeled peptides and proteins, and reduces non-specific binding. Two different single molecular weight dPEG® spacers are available for precise spatial control between the modified biotin and the surface of the molecule to which it is conjugated. |
Legal Information: | dPEG is a registered trademark of Quanta BioDesign |
Legal Information: | Products Protected under U.S. Patents # 7,888,536 B2 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | >90% |
Storage Temp. | −20°C |
UNSPSC | 12352200 |