MAL-dPEG®8-acid
ALDRICH/QBD10275 - >95% (HPLC)
Synonym: Carboxy-
Empirical Formula (Hill Notation): C26H44N2O13
Molecular Weight: 592.63
MDL Number: MFCD13184956
Linear Formula: C26H44N2O13
Product Type: Chemical
| assay | >95% (HPLC) |
| form | solid or viscous liquid |
| polymer architecture | shape : linear functionality : heterobifunctional |
| reaction suitability | reaction type: Pegylations |
| shipped in | ambient |
| storage temp. | −20°C |
| Features and Benefits: | MAL-dPEG8-acid is a monodisperse crosslinker that joins sulfhydryl groups to free amines through a single molecular weight polyethylene glycol (PEG) chain of discrete length. The linker is 34 atoms and 38.8 Å long. The maleimidopropyl moiety reacts with sulfhydryl groups via a Michael addition reaction. The propionic acid terminus of the molecule reacts directly with free amines using EDC or another carbodiimide to form amide bonds. Alternatively, activation of the propionic acid group with N-hydroxysuccinimide (NHS), 2,3,5,6-tetrafluorophenol (TFP), or some other acylating agent permits amide bond formation under mild, controlled conditions. |
| Legal Information: | dPEG is a registered trademark of Quanta BioDesign |
| Legal Information: | Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681 |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | >95% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |