DBCO-dPEG ®12-MAL
ALDRICH/QBD10593
Synonym: Polyethylene glycol
Empirical Formula (Hill Notation): C52H74N4O17
Molecular Weight: 1027.16
Linear Formula: C52H74N4O17
Product Type: Chemical
assay | >90% |
form | solid or viscous liquid |
polymer architecture | shape : linear functionality : heterobifunctional |
reaction suitability | reagent type: cross-linking reagent reaction type: click chemistry |
shipped in | ambient |
SMILES string | O=C(CCOCCOCCOCCOCCOCCOCCO |
storage temp. | −20°C |
Features and Benefits: | DBCO-dPEG ®₁₂-MAL can be used to conjugate two different proteins or an antibody with a payload by using copper-free "click" chemistry with the DBCO and reaction of the maleimide with a free thiol. |
General description: | DBCO-dPEG®12-MAL is a versatile heterobifunctional cross-linking reagent used in strain-promoted azide-alkyne cycloaddition (SPAAC) reaction. This approach is also known as copper-free click chemistry. The presence of maleimidopropyl (MAL) functional group in the reagent forms a thiol-ether linkage with sulfhydryl groups. |
Legal Information: | dPEG is a registered trademark of Quanta BioDesign |
Legal Information: | Products Protected under U.S. Patents # 7,888,536 B2 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | >90% |
Storage Temp. | −20°C |
UNSPSC | 51171641 |