NHS-dPEG^®₂₄-biotin

ALDRICH/QBD10774

Synonym: Polyethylene glycol

Empirical Formula (Hill Notation): C₆₅H₁₂₀N₄O₃₀S
Molecular Weight: 1469.72
Linear Formula: C₆₅H₁₂₀N₄O₃₀S
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-QBD10774-50MG	50 mg	$370.00 1/EAAdd To Favorites		Add To Favorites
45-QBD10774-1000MG	1000 mg	$2110.00 1/EAAdd To Favorites		Add To Favorites

assay	>90%
form	solid or viscous liquid
polymer architecture	shape : linear functionality : monofunctional
reaction suitability	reaction type: Biotinylations reactivity: amine reactive
	reagent type: cross-linking reagent
shipped in	ambient
SMILES string	O=C(CCCCC1SCC(N2)C1NC2=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON3C(CCC3=O)=O)=O
storage temp.	−20°C

Features and Benefits:	NHS-dPEG^®₂₄-biotin is used extensively to label molecules that contain a free amine with biotin. The single molecular weight NHS-dPEG^®₂₄-biotin compound has a long spacer of precise length (97.7 Å) between the biotin moiety and the labeled molecule. This dPEG^® spacer imparts a high degree of water solubility to the biotin label. For biotinylated peptides and proteins, the dPEG^® spacer dramatically reduces aggregation and precipitation of the modified molecule and reduces non-specific binding of the molecule, both of which are common problems with molecules that have been biotinylated with the widely used NHS-LC-biotin.
General description:	NHS-dPEG^®₂₄-biotin is a cross-linking reagent used in biotinylation reactions. The N-hydroxysuccinimidyl (NHS) moiety of NHS-dPEG^®₂₄-biotin forms a stable amide bond with free primary amines, such as the amines on the side chain of lysine. The biotin moiety is used in a variety of applications, including labeling, supramolecular building, affinity chromatography, pull-down assays, and the production of biotinylated antibodies.
Legal Information:	dPEG is a registered trademark of Quanta BioDesign
Legal Information:	Products Protected under U.S. Patents # 7,888,536 B2