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NHS-dPEG®24-biotin

ALDRICH/QBD10774

Synonym: Polyethylene glycol

Empirical Formula (Hill Notation): C65H120N4O30S
Molecular Weight: 1469.72
Linear Formula: C65H120N4O30S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-QBD10774-50MG 50 mg
 $370.00
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45-QBD10774-1000MG 1000 mg
 $2110.00
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assay >90%
form solid or viscous liquid
InChI 1S/C65H120N4O30S/c70-60(4-2-1-3-59-64-58(57-100-59)67-65(74)68-64)66-8-10-76-12-14-78-16-18-80-20-22-82-24-26-84-28-30-86-32-34-88-36-38-90-40-42-92-44-46-94-48-50-96-52-54-98-56-55-97-53-51-95-49-47-93-45-43-91-41-39-89-37-35-87-33-31-85-29-27-83-25-23-8
InChI key FWKPYGZMJFADHK-UHFFFAOYSA-N
polymer architecture shape : linear
functionality : monofunctional
reaction suitability reaction type: Biotinylations
reactivity: amine reactive
  reagent type: cross-linking reagent
shipped in ambient
SMILES string O=C(CCCCC1SCC(N2)C1NC2=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON3C(CCC3=O)=O)=O
storage temp. −20°C
Features and Benefits: NHS-dPEG®24-biotin is used extensively to label molecules that contain a free amine with biotin. The single molecular weight NHS-dPEG®24-biotin compound has a long spacer of precise length (97.7 Å) between the biotin moiety and the labeled molecule. This dPEG® spacer imparts a high degree of water solubility to the biotin label. For biotinylated peptides and proteins, the dPEG® spacer dramatically reduces aggregation and precipitation of the modified molecule and reduces non-specific binding of the molecule, both of which are common problems with molecules that have been biotinylated with the widely used NHS-LC-biotin.
General description: NHS-dPEG®24-biotin is a cross-linking reagent used in biotinylation reactions. The N-hydroxysuccinimidyl (NHS) moiety of NHS-dPEG®24-biotin forms a stable amide bond with free primary amines, such as the amines on the side chain of lysine. The biotin moiety is used in a variety of applications, including labeling, supramolecular building, affinity chromatography, pull-down assays, and the production of biotinylated antibodies.
Legal Information: dPEG is a registered trademark of Quanta BioDesign
Legal Information: Products Protected under U.S. Patents # 7,888,536 B2
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity >90%
Storage Temp. −20°C
UNSPSC 51171641

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