Thiol-dPEG®12-acid
ALDRICH/QBD10850 - >95% (HPLC)
Synonym: CT(PEG)12; Carboxy-PEG-Thiol; Carboxy-PEG12-Thiol; HS-PEG12-COOH; Thiol-PEG12-acid
Empirical Formula (Hill Notation): C27H54O14S
Molecular Weight: 634.77
MDL Number: MFCD21363238
Linear Formula: C27H54O14S
Product Type: Chemical
assay | >95% (HPLC) |
form | solid or viscous liquid |
polymer architecture | shape : linear functionality : heterobifunctional |
reaction suitability | reaction type: Pegylations |
shipped in | ambient |
storage temp. | −20°C |
Features and Benefits: | Thiol-dPEG12-acid is a single molecular weight, discrete-length polyethylene glycol (dPEG) crosslinking PEGylation reagent. One end of the crosslinker terminates in a sulfhydryl (thiol) group. Propionic acid terminates the opposite end. The thiol end of the molecule forms dative bonds with gold. Moreover, it forms thioether bonds with maleimide and bromoacetate groups and disulfide bonds with other sulfhydryl groups. The propionic acid group reacts with amines to form amide bonds. Alternatively, if it is left unreacted, the propionic acid group provides a negative charge to the conjugated molecule or modified surface. The monodispersed dPEG spacer is 39 atoms (46.8 Å) long. |
Legal Information: | dPEG is a registered trademark of Quanta BioDesign |
Legal Information: | Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681 |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | >95% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |