SPDP-dPEG®36-NHS ester
ALDRICH/QBD10867 - >95% (HPLC)
Synonym: OPSS-PEG1500-NHS ester; OPSS-PEG36-NHS ester; SPDP-PEG-NHS ester; SPDP-PEG36-NHS ester
Empirical Formula (Hill Notation): C87H161N3O41S2
Molecular Weight: 1969.33
MDL Number: MFCD21363283
Linear Formula: C87H161N3O41S2
Product Type: Chemical
| assay | >95% (HPLC) |
| form | solid or viscous liquid |
| polymer architecture | shape : linear functionality : heterobifunctional |
| reaction suitability | reaction type: Pegylations |
| shipped in | ambient |
| storage temp. | −20°C |
| Features and Benefits: | SPDP-dPEG36-NHS ester is an amphiphilic, water-soluble PEGylation reagent that is designed to crosslink amines and free thiols. SPDP (also referred to as orthopyridyl disulfide, or OPSS) reacts with sulfhydryl groups to form disulfide bonds. The N-hydroxysuccinimidyl (NHS) ester reacts with free amines to form amide bonds. The single molecular weight, discrete chain length polyethylene glycol (dPEG) chain is 115 atoms (137.8 Å) long. SPDP-dPEG36-NHS ester is used like SPDP and its related hydrophobic products. However, the water-soluble dPEG product prevents hydrophobicity-triggered precipitation of compounds to which it is conjugated. SPDP-dPEG36-NHS ester is a monodisperse equivalent of the polymeric PEG1500. |
| Legal Information: | dPEG is a registered trademark of Quanta BioDesign |
| Legal Information: | Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681 |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | >95% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |