Thioacetic acid
ALDRICH/T30805 - 96%
Synonym: TAA; TMA; Thiacetic acid
CAS Number: 507-09-5
Empirical Formula (Hill Notation): C2H4OS
Molecular Weight: 76.12
EC Number: 208-063-8
MDL Number: MFCD00004853
Linear Formula: CH3COSH
Product Type: Chemical
assay | 96% |
bp | 88-91.5 °C (lit.) |
density | 1.065 g/mL at 25 °C (lit.) |
InChI | 1S/C2H4OS/c1-2(3)4/h1H3,( |
InChI key | DUYAAUVXQSMXQP-UHFFFAOYSA |
Quality Level | 200 ![]() |
refractive index | n |
SMILES string | CC(S)=O |
storage temp. | 2-8°C |
Application: | Thioacetic acid (TAA) can undergo: • Enantioselective addition to nitroalkenes to form chiral 1,2-aminothiol derivatives in the presence of a novel sulfinyl urea organocatalyst. This method has been successfully employed in the synthesis of antifungal drug, sulconazole. • Asymmetric Michael addition reaction with chalcones in the presence of a bifunctional amine thiourea catalyst to form synthetically useful thioesters. • Asymmetric 1,6-conjugate addition with para-quinone methides in the presence of a chiral phosphoric acid catalyst to form chiral sulfur-containing diphenylmethane-type compounds. • Conjugate addition to methacrylamides with chiral trans-2,5-disubstituted pyrrolidine auxiliaries to form chiral β-mercaptocarboxylic acid derivatives. |
Application: | Thioacetic acid is a reagent for introduction of the thiol group into organic molecules. |
Packaging: | 5, 100, 500 g in glass bottle |
Symbol | ![]() ![]() ![]() |
Signal word | Danger |
Hazard statements | H225 - H301 - H317 - H318 - H332 |
Precautionary statements | P210 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338 |
Hazard Codes | F,Xn |
Risk Statements | 11-34-41-43 |
Safety Statements | 9-16-26-36/37/39-45 |
RIDADR | UN 2436 3 / PGII |
WGK Germany | WGK 3 |
Flash Point(F) | 64.4 °F |
Flash Point(C) | 18 °C |
Purity | 96% |
bp | 88-91.5 °C (lit.) |
Density | 1.065 g/mL at 25 °C (lit.) |
Refractive Index | n |
Storage Temp. | 2-8°C |
UNSPSC | 12352106 |