2,2,2-Trichloroethanol
ALDRICH/T54801 - ReagentPlus®, ≥99%
Synonym: Trichloroethyl alcohol
CAS Number: 115-20-8
Empirical Formula (Hill Notation): C2H3Cl3O
Molecular Weight: 149.40
EC Number: 204-071-0
MDL Number: MFCD00004677
Linear Formula: Cl3CCH2OH
Product Type: Chemical
| assay | ≥99% |
| bp | 152-154 °C (lit.) |
| density | 1.56 g/mL at 20 °C (lit.) |
| InChI | 1S/C2H3Cl3O/c3-2(4,5)1-6/ |
| InChI key | KPWDGTGXUYRARH-UHFFFAOYSA |
| mp | 17.8 °C (lit.) |
| product line | ReagentPlus® |
| Quality Level | 200  |
| refractive index | n |
| SMILES string | OCC(Cl)(Cl)Cl |
| vapor density | 5.16 (vs air) |
| vapor pressure | 1 mmHg ( 20 °C) |
| Application: | The 2,2,2-Trichloroethyl (TCE) moiety of 2,2,2-trichloroethanol is mainly used as a protecting group for acids, acetals and also phosphoryl groups of nucleotides. It can be easily cleaved by zinc reduction. Some of its other application include: • Conversion of per-O-acetylated sugars to per-O-acetylated trichloroethyl derivatives. • Preparation of TCE ester of chlorosulfuric acid. • Preparation of 2,2,2-trichloroethyl acetimidate hydrochloride. |
| Legal Information: | ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Packaging: | 100, 500 g in glass bottle |
| Symbol |   GHS05,GHS07 |
| Signal word | Danger |
| Hazard statements | H302 - H318 - H336 |
| Precautionary statements | P261 - P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 |
| Hazard Codes | Xn |
| Risk Statements | 22-41-67 |
| Safety Statements | 26-39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | 230.0 °F - closed cup |
| Flash Point(C) | 110 °C - closed cup |
| Purity | ≥99% |
| bp | 152-154 °C (lit.) |
| mp | 17.8 °C (lit.) |
| Density | 1.56 g/mL at 20 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12352100 |