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3,3′,5-Triiodothyroacetic acid

ALDRICH/T7650 - ≥90%

Synonym: 4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenylacetic acid

CAS Number: 51-24-1
Empirical Formula (Hill Notation): C14H9I3O4
Molecular Weight: 621.93
EC Number: 200-086-1
MDL Number: MFCD00055931
Linear Formula: C14H9I3O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-T7650-100MG 100 mg
 $148.00
1/EA		 Add To Favorites
45-T7650-500MG 500 mg
 $391.00
1/EA		 Add To Favorites
45-T7650-1G 1 g
 $681.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: T7650-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: T7650-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: T7650-500MG

 

assay ≥90%
form powder
InChI 1S/C14H9I3O4/c15-9-6-8(1-2-12(9)18)21-14-10(16)3-7(4-11(14)17)5-13(19)20/h1-4,6,18H,5H2,(H,19,20)
InChI key UOWZUVNAGUAEQC-UHFFFAOYSA-N
Quality Level 200 
SMILES string OC(=O)Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1
storage temp. −20°C
Application:

  • Thyroid hormone research: A study explored the impact of 3,3′,5-Triiodothyroacetic acid on peripheral and neurodevelopmental findings in patients with MCT8 deficiency, highlighting its potential in therapeutic interventions for thyroid-related developmental disorders (Unsal and Hayran, 2024 ).

  • Neurological disorder management: Research demonstrated the use of 3,3′,5-Triiodothyroacetic acid in addressing impaired T3 uptake and action in cerebral organoids modeling Allan-Herndon-Dudley syndrome, providing insights into its application in managing brain-specific thyroid hormone transport abnormalities (Salas-Lucia et al., 2024 ).

  • Pharmaceutical development for antiviral therapies: Tiratricol, a derivative of 3,3′,5-Triiodothyroacetic acid, was identified as an inhibitor of yellow fever virus replication by targeting the viral RNA-dependent RNA polymerase, showcasing its potential in antiviral drug development (Ren et al., 2023 ).
Packaging: 1 g in poly bottle
Packaging: 100, 500 mg in poly bottle
Purity ≥90%
Storage Temp. −20°C
UNSPSC 12352100

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