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D-(+)-Vesamicol hydrochloride

ALDRICH/V104 - solid

CAS Number: 112709-60-1
Empirical Formula (Hill Notation): C17H25NO · HCl
Molecular Weight: 295.85
MDL Number: MFCD00069370
Linear Formula: C17H25NO · HCl
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-V104-10MG 10 mg
$99.00
1/EA
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color white
form solid
InChI 1S/C17H25NO.ClH/c19-17-9-5-4-8-16(17)18-12-10-15(11-13-18)14-6-2-1-3-7-14;/h1-3,6-7,15-17,19H,4-5,8-13H2;1H/t16-,17-;/m0./s1
InChI key XJNUHVMJVWOYCW-QJHJCNPRSA-N
Quality Level 100 
SMILES string Cl.O[C@H]1CCCC[C@@H]1N2CCC(CC2)c3ccccc3
solubility DMSO: soluble
  ethanol: soluble
Application: D-(+)-Vesamicol hydrochloride can be used as a reactant to prepare:
•  Trialkylstannyl vesamicol analogs as potent vesicular acetylcholine transporters (VAChTs) and sigma receptors.
•  Vesamicol analog, (+)-2-[4-(4-iodophenyl)piperidino] cyclohexanol as a possible tumor imaging agent.

Biochem/physiol Actions: Less active enantiomer of vesamicol
General description: D-(+)-Vesamicol is a potent inhibitor of acetycholine transport into the synaptic vesicles in cholinergic nerve terminals. It is 25-times less potent than the L-form.
Packaging: 10 mg in poly bottle
UNSPSC 12352005

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