trans-Anethole

ALDRICH/W208604 - ≥99%, FCC, FG

Synonym: 4-Propenylanisole; trans-1-Methoxy-4-(1-propenyl)benzene

CAS Number: 4180-23-8
Empirical Formula (Hill Notation): C₁₀H₁₂O
Molecular Weight: 148.20
EC Number: 224-052-0
MDL Number: MFCD00009284
Linear Formula: CH₃CH=CHC₆H₄OCH₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-W208604-SAMPLE-K	1 each	$58.00 1/EA	Add To Favorites
45-W208604-1KG-K	1 kg	$143.00 1/EA	Add To Favorites
45-W208604-5KG-K	5 kg	$437.00 1/EA	Add To Favorites
45-W208604-10KG-K	10 kg	$696.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

agency	follows IFRA guidelines
	meets purity specifications of JECFA
application(s)	flavors and fragrances
assay	≥99%
biological source	synthetic
bp	234-237 °C (lit.)
density	0.988 g/mL at 25 °C (lit.)
documentation	see Safety & Documentation for available documents
food allergen	no known allergens
form	liquid
fragrance allergen	trans-anethole
grade	FG
	Fragrance grade
	Halal
	Kosher
InChI	1S/C10H12O/c1-3-4-9-5-7-10(11-2)8-6-9/h3-8H,1-2H3/b4-3+
InChI key	RUVINXPYWBROJD-ONEGZZNKSA-N
mp	20-21 °C (lit.)
organoleptic	anise; sweet
Quality Level	300
	400
refractive index	n20/D 1.561 (lit.)
reg. compliance	EU Regulation 1223/2009
	EU Regulation 1334/2008 & 178/2002
	FCC
	FDA 21 CFR 117
	FDA 21 CFR 182.60
SMILES string	COc1ccc(C=CC)cc1

Application:	Anti-oral streptococci and anti-biofilm properties of Etlingera pavieana essential oil and its bioactive compounds proposed for an alternative herbal mouthwash.: This study evaluates the antimicrobial properties of Etlingera pavieana essential oil, identifying trans-anethole as a key bioactive compound with potential applications in oral hygiene products (Wongsariya et al., 2024 ). Efficacy and safety of aniseed powder for treating gastrointestinal symptoms of COVID-19: a randomized, placebo-controlled trial.: The trial highlights the therapeutic potential of aniseed powder, rich in trans-anethole, for alleviating gastrointestinal symptoms in COVID-19 patients (Mosaffa-Jahromi et al., 2024 ). Transcriptomic and biochemical analyses revealed antifungal mechanism of trans-anethole on Aspergillus flavus growth.: This research elucidates the antifungal mechanism of trans-anethole against Aspergillus flavus, suggesting its potential application in controlling fungal contamination in food and agriculture (Lei et al., 2023 ).
Biochem/physiol Actions:	Naturally occurring phenylpropene derivative that is estrogenic at lower concentrations and cytotoxic at higher concentrations to cancer cell lines. The cytotoxicity is related to the metabolism of trans-anethole to 4-hydroxy-1-propenylbenzene.
Packaging:	1 kg in aluminum bottle
Packaging:	10 kg in composite drum
Packaging:	5 kg in steel drum

Symbol	GHS07,GHS09
Signal word	Warning
Hazard statements	H317 - H411
Precautionary statements	P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
Hazard Codes	Xi
Risk Statements	43
Safety Statements	36/37
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	213.8 °F
Flash Point(C)	101 °C

Purity	≥99%
bp	234-237 °C (lit.)
mp	20-21 °C (lit.)
Density	0.988 g/mL at 25 °C (lit.)
Refractive Index	n20/D 1.561 (lit.)
FEMA Number	2086
UNSPSC	12164502

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