Synonym: (1R,2S,5R)-(−)-Menthol; (−)-Menthol; (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol; 5-Methyl-2-(1-methylethyl)cyclohexanol
CAS Number: 2216-51-5
Empirical Formula (Hill Notation): C10H20O
Molecular Weight: 156.27
EC Number: 218-690-9
MDL Number: MFCD00062979
Linear Formula: C10H20O
Product Type: Chemical
| application(s) |
flavors and fragrances |
| assay |
≥99% |
| biological source |
synthetic |
| bp |
212 °C (lit.) |
| density |
0.89 g/mL at 25 °C (lit.) |
| documentation |
see Safety & Documentation for available documents |
| food allergen |
no known allergens |
| grade |
FG |
| |
Kosher |
| InChI |
1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3/t8-,9+,10-/m1/s1 |
| InChI key |
NOOLISFMXDJSKH-KXUCPTDWSA-N |
| mp |
41-45 °C (lit.) |
| optical activity |
[α]22/D −49°, c = 10 in 95% ethanol |
| organoleptic |
cooling; minty; camphoraceous |
| Quality Level |
400  |
| reg. compliance |
EU Regulation 1334/2008 & 178/2002 |
| |
FCC |
| |
FDA 21 CFR 117 |
| |
FDA 21 CFR 172.515 |
| SMILES string |
CC(C)[C@@H]1CC[C@@H](C)C[C@H]1O |
| vapor pressure |
0.8 mmHg ( 20 °C) |
| Application: |
- Chemical Characterization of Terpene-Based Hydrophobic Eutectic Solvents and Their Application for Pb(II) Complexation during Solvent Extraction Procedure.: Explores the use of l-menthol-based hydrophobic eutectic solvents for efficient heavy metal extraction, highlighting its potential in environmental clean-up and recovery of valuable metals from waste streams (Suljkanović et al., 2024
 ).
- Eco-Friendly Production of Boron Nitride Nanosheets via Deep Eutectic Solvents and Their Application in Enhancing Thermal Conductivity of PVDF Composites.: Investigates l-menthol′s role in synthesizing boron nitride nanosheets using green chemistry approaches, enhancing the material properties of composites used in electronics and engineering applications (Sang et al., 2024 ).
- Supramolecular Structure of the β-Cyclodextrin Metal-Organic Framework Optimizes Iodine Stability and Its Co-delivery with l-Menthol for Antibacterial Applications.: Demonstrates the novel use of l-menthol in conjunction with metal-organic frameworks for developing advanced antibacterial delivery systems, offering enhanced stability and efficacy in medical and health care products (Zhao et al., 2024 ).
- Acid-based deep eutectic solvents followed by GFAAS for the speciation of As(III), As(V), total inorganic arsenic and total arsenic in rice samples.: Utilizes l-menthol in innovative solvent systems for arsenic speciation, contributing to safer food production and effective monitoring of contaminants in agricultural products (Fattahi et al., 2024 ).
|
| Biochem/physiol Actions: |
Taste at 25 ppm |
| General description: |
Natural occurrence: Mentha species. |
| General description: |
L-Menthol is the principal component of peppermint oil. It is widely used in confectionaries cosmetics and toothpaste for its characteristic peppermint flavor and cooling effect. |
| Other Notes: |
The substance W266590 has no REACH registration because the only supported use is the use in medicinal products for human or veterinary use or in food or feedingstuffs according to article 2 of the REACH Regulation (EC) No 1907/2006. |
| Packaging: |
1 kg in poly bottle |
| Packaging: |
4, 25 kg in fiber drum |
| Purity |
≥99% |
| bp |
212 °C (lit.) |
| mp |
41-45 °C (lit.) |
| Density |
0.89 g/mL at 25 °C (lit.) |
| FEMA Number |
2665 |
| UNSPSC |
12164502 |
GHS07