2,3,5,6-Tetramethylpyrazine

ALDRICH/W323713 - natural, ≥98%, FG

Synonym: Chuanxingzine; Ligustrazine; Tetrapyrazine

CAS Number: 1124-11-4
Empirical Formula (Hill Notation): C₈H₁₂N₂
Molecular Weight: 136.19
EC Number: 214-391-2
MDL Number: MFCD00006146
Linear Formula: C₈H₁₂N₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-W323713-100G-K	100 g	$378.00 1/EAAdd To Favorites	Add To Favorites
45-W323713-1KG-K	1 kg	$2860.00 1/EAAdd To Favorites	Add To Favorites
45-W323713-SAMPLE-K		$58.50 1/EAAdd To Favorites	Add To Favorites

agency	follows IFRA guidelines
	meets purity specifications of JECFA
application(s)	flavors and fragrances
assay	≥98%
bp	190 °C (lit.)
documentation	see Safety & Documentation for available documents
food allergen	no known allergens
fragrance allergen	no known allergens
grade	FG
	Fragrance grade
	Halal
	Kosher
	natural
greener alternative category	, Aligned
greener alternative product characteristics	Less Hazardous Chemical Syntheses Use of Renewable Feedstocks Learn more about the Principles of Green Chemistry .
impurities	≤2.0% water (Karl Fischer)
InChI	1S/C8H12N2/c1-5-6(2)10-8(4)7(3)9-5/h1-4H3
InChI key	FINHMKGKINIASC-UHFFFAOYSA-N
mp	77-80 °C (lit.)
organoleptic	chocolate; coffee; fatty; musty; nutty
Quality Level	400
reg. compliance	EU Regulation 1223/2009
	EU Regulation 1334/2008 & 178/2002
SMILES string	Cc1nc(C)c(C)nc1C
sustainability	Greener Alternative Product

Application:	Booklice Liposcelis bostrychophila are efficiently attracted by the combination of 2,3,5,6-tetramethylpyrazine and ultraviolet light.: This study demonstrates that the combination of 2,3,5,6-tetramethylpyrazine and ultraviolet light effectively attracts booklice, suggesting a potential application for pest management in stored product environments (Tanaka et al., 2024 ). 2,3,5,6-Tetramethylpyrazine protects retinal photoreceptors against endoplasmic reticulum stress by modulating ATF4-mediated inhibition of PRP aggregation.: The research highlights the neuroprotective effects of 2,3,5,6-tetramethylpyrazine, showing its potential in treating retinal diseases by protecting photoreceptors from stress-induced damage (Huang et al., 2021 ). Tetramethylpyrazine-Inducible Promoter Region from Rhodococcus jostii TMP1.: The study identifies a promoter region in Rhodococcus jostii TMP1 that is inducible by tetramethylpyrazine, which could be utilized in genetic engineering and biotechnology applications (Stanislauskienė et al., 2018 ).
General description:	2,3,5,6-Tetramethylpyrazine is one of the main volatile aroma compounds in roasted cocoa beans and maple syrup.
General description:	We are committed to bringing you Greener Alternative Products, which adhere to one of the four categories of Greener Alternatives . This product is a Biobased products, showing key improvements in Green Chemistry Principles “Less Hazardous Chemical Syntheses” and “Use of Renewable Feedstock”.
Packaging:	1 kg in poly bottle
Packaging:	25, 100 g in poly bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H302 - H315 - H319 - H335
Precautionary statements	P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
Hazard Codes	Xn
Risk Statements	22-37/38-41
Safety Statements	26-39
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98%
bp	190 °C (lit.)
mp	77-80 °C (lit.)
FEMA Number	3237
UNSPSC	12164502