4-Hydroxybutanoic acid lactone
ALDRICH/W329118 - ≥98%, FCC, FG
Synonym: γ-Butyrolactone; γ-Hydroxybutyric acid lactone; 4-Hydroxybutyric acid lactone; GBL
CAS Number: 96-48-0
Empirical Formula (Hill Notation): C4H6O2
Molecular Weight: 86.09
EC Number: 202-509-5
MDL Number: MFCD00005386
Linear Formula: C4H6O2
Product Type: Chemical
| agency | follows IFRA guidelines |
| meets purity specifications of JECFA | |
| application(s) | flavors and fragrances |
| assay | ≥98% |
| autoignition temp. | 851 °F |
| biological source | synthetic |
| bp | 204-205 °C (lit.) |
| density | 1.12 g/mL at 25 °C (lit.) |
| documentation | see Safety & Documentation for available documents |
| expl. lim. | 16 % |
| food allergen | no known allergens |
| fragrance allergen | no known allergens |
| grade | FG |
| Fragrance grade | |
| Halal | |
| Kosher | |
| InChI | 1S/C4H6O2/c5-4-2-1-3-6-4/ |
| InChI key | YEJRWHAVMIAJKC-UHFFFAOYSA |
| mp | −45 °C (lit.) |
| organoleptic | caramel; creamy; fatty; oily |
| Quality Level | 400  |
| refractive index | n |
| reg. compliance | EU Regulation 1223/2009 |
| EU Regulation 1334/2008 & 178/2002 | |
| FCC | |
| FDA | |
| SMILES string | O=C1CCCO1 |
| vapor density | 3 (vs air) |
| vapor pressure | 1.5 mmHg ( 20 °C) |
| Application: |
|
| Biochem/physiol Actions: | Precursor of γ-hydroxybutyric acid (GHB). It blocks dopamine release by blocking impulse flow in dopaminergic neurons. Pretreatment with γ-butyrolactone allows detection of autoreceptor-induced dopamine release. |
| Packaging: | 1 drum in steel drum |
| Packaging: | 1 kg in poly bottle |
| Packaging: | 10, 25 kg in poly drum |
).| Symbol |   GHS05,GHS07 |
| Signal word | Danger |
| Hazard statements | H302 - H318 - H336 |
| Precautionary statements | P261 - P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 |
| Hazard Codes | Xn |
| Risk Statements | 22-41-67 |
| Safety Statements | 26-39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | 208.4 °F - closed cup |
| Flash Point(C) | 98 °C - closed cup |
| Purity | ≥98% |
| bp | 204-205 °C (lit.) |
| mp | −45 °C (lit.) |
| Density | 1.12 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| FEMA Number | 3291 |
| UNSPSC | 12164502 |