(3aR)-(+)-Sclareolide
ALDRICH/W379401 - natural, 97%, FG
Synonym: Sclareolide
CAS Number: 564-20-5
Empirical Formula (Hill Notation): C16H26O2
Molecular Weight: 250.38
EC Number: 209-269-0
MDL Number: MFCD00134168
Linear Formula: C16H26O2
Product Type: Chemical
12 Principles of Green Chemistry: Principle 3—Less Hazardous Chemical Syntheses. This product manufacturing process was designed with lesser toxicity to human health and the environment.
12 Principles of Green Chemistry: Principle 7—A raw material or feedstock should be renewable rather than depleting whenever technically and economically practicable.
| agency | follows IFRA guidelines |
| application(s) | flavors and fragrances |
| assay | 97% |
| biological source | Salvia sclarea L |
| documentation | see Safety & Documentation for available documents |
| food allergen | no known allergens |
| fragrance allergen | sclareol |
| grade | FG |
| Fragrance grade | |
| natural | |
| greener alternative category | Aligned  |
| greener alternative product characteristics | Less Hazardous Chemical Syntheses Use of Renewable Feedstocks Learn more about the Principles of Green Chemistry . |
| impurities | may contain ≤0.10% 2-Methylpentane (residual solvent) |
| InChI | 1S/C16H26O2/c1-14(2)7-5-8 |
| InChI key | IMKJGXCIJJXALX-SHUKQUCYSA |
| mp | 124-126 °C (lit.) |
| organoleptic | woody; paper |
| Quality Level | 400 |
| reg. compliance | EU Regulation 1223/2009 |
| EU Regulation 1334/2008 & 872/2012 | |
| FDA 21 CFR 110 | |
| SMILES string | [H][C@@]12CC[C@@]3(C)OC(= |
| sustainability | Greener Alternative Product |
| Application: | • Approach to Merosesquiterpenes via Lewis Acid Catalyzed Nazarov-Type Cyclization.: The synthesis of "(3aR)-(+)-Sclareolide" plays a crucial role in the total synthesis of Akaol A, a merosesquiterpene. This compound is utilized in studies focusing on Lewis acid-catalyzed Nazarov-type cyclization, which is a key reaction for constructing complex cyclic structures within organic molecules. This synthesis process not only expands the capabilities of chemists to build intricate molecular architectures but also enhances the understanding of reaction mechanisms crucial for pharmaceutical development (DOI: 10.1021/acs.orglett.6b004 ). |
| General description: | We are committed to bringing you greener alternative products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is Biobased and thus aligns with "Less Hazardous Chemical Syntheses" and "Use of Renewable Feedstocks". |
| Packaging: | 25, 100 g in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 97% |
| mp | 124-126 °C (lit.) |
| FEMA Number | 3794 |
| UNSPSC | 12164502 |