Sucrose acetate isobutyrate

ALDRICH/W518107

Synonym: SAIB

Empirical Formula (Hill Notation): C₄₀H₆₂O₁₉
Molecular Weight: 846.91
MDL Number: MFCD00041859
Linear Formula: C₄₀H₆₂O₁₉
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-W518107-1KG-K	1 kg	$0.00 1/EA CALL FOR PRICE		Add To Favorites
45-W518107-SAMPLE-K		$65.60 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

application(s)	flavors and fragrances
biological source	synthetic
bp	288 °C
density	1.146 g/mL at 25 °C
documentation	see Safety & Documentation for available documents
food allergen	no known allergens
grade	Kosher
InChI	1S/C40H62O19/c1-18(2)33(43)51-17-40(32(57-38(48)23(11)12)29(54-35(45)20(5)6)27(58-40)16-50-25(14)42)59-39-31(56-37(47)22(9)10)30(55-36(46)21(7)8)28(53-34(44)19(3)4)26(52-39)15-49-24(13)41/h18-23,26-32,39H,15-17H2,1-14H3/t26-,27-,28-,29-,30+,31-,32+,39-,40+/m1/s1
InChI key	ZNEBZIJCDDCNRC-SWTLDUCYSA-N
organoleptic	odorless
Quality Level	400
SMILES string	CC(C)C(=O)OC[C@]1(O[C@H](COC(C)=O)[C@@H](OC(=O)C(C)C)[C@@H]1OC(=O)C(C)C)O[C@H]2O[C@H](COC(C)=O)[C@@H](OC(=O)C(C)C)[C@H](OC(=O)C(C)C)[C@H]2OC(=O)C(C)C

Application:	An ultrasound-triggered injectable sodium alginate scaffold loaded with electrospun microspheres for on-demand drug delivery to accelerate bone defect regeneration.: This study highlights the use of Sucrose Acetate Isobutyrate (SAIB) in developing advanced drug delivery systems. SAIB is utilized to enhance the stability and controlled release properties of drug-loaded microspheres integrated into sodium alginate scaffolds, offering precise therapeutic management in bone regeneration applications (Yi Y et al., 2024 ). Sustained Release of Dexamethasone from 3D-Printed Scaffolds Modulates Macrophage Activation and Enhances Osteogenic Differentiation.: Incorporating SAIB into 3D-printed scaffolds has shown to effectively control the release rates of dexamethasone, a therapeutic agent, facilitating improved osteogenic differentiation and reduced inflammatory responses, crucial for bone healing and regeneration (Majrashi M et al., 2023 ). Application of Sucrose Acetate Isobutyrate in Development of Co-Amorphous Formulations of Tacrolimus for Bioavailability Enhancement.: Research demonstrates how SAIB can be used to develop co-amorphous drug formulations, specifically for tacrolimus, to enhance its bioavailability. This approach addresses significant challenges in drug solubility and stability, marking a significant advance in the formulation of poorly water-soluble drugs (Mohamed EM et al., 2023 ).
Disclaimer:	For R&D or non-EU Food use. Not for retail sale.
Packaging:	1 kg in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

bp	288 °C
Density	1.146 g/mL at 25 °C
UNSPSC	12164502

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