Mitomycin C

ROCHE/10107409001 - crystalline powder, 98%, pkg of 2 mg

Synonym: Mitomycin C

CAS Number: 50-07-7
Empirical Formula (Hill Notation): C₁₅H₁₈N₄O₅
Molecular Weight: 334.33
Linear Formula: C₁₅H₁₈N₄O₅
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-10107409001	2 mg	$129.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

antibiotic activity spectrum	Gram-negative bacteria
	Gram-positive bacteria
assay	98%
form	crystalline powder
InChI	1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1
InChI key	NWIBSHFKIJFRCO-WUDYKRTCSA-N
manufacturer/tradename	Roche
mode of action	DNA synthesis \| interferes
mol wt	334.3
packaging	pkg of 2 mg
Quality Level	100
storage temp.	2-8°C

Application:	Mitomycin C has been used: • to cease mitosis • in phosphate buffer saline (PBS) for inactivation and plating mouse embryonic fibroblasts (MEFs) • as mutagen in mutagenicity assay
Application:	Mitomycin C is used as an inhibitor for studies of cell-free protein biosynthesis. It also inhibits DNA synthesis. It has been used as a genotoxic agent for tumor cells.
Biochem/physiol Actions:	Mitomycin C (MMC) acts as a prototype for drugs with bioreductive alkylation. It is mainly found to be active under anaerobic conditions. MMC exhibits a vast clinical antitumor spectrum effectively in gastric, pancreatic and breast cancer.
General description:	Mitomycin C is an antitumor antibiotic.
Other Notes:	For life science research only. Not for use in diagnostic procedures.

Symbol	GHS06,GHS08
Signal word	Danger
Hazard statements	H300 - H351
Precautionary statements	P201 - P264 - P280 - P301 + P310 + P330 - P308 + P313 - P501
RIDADR	UN 2811 6.1 / PGII
WGK Germany	WGK 3
Flash Point(F)	does not flash
Flash Point(C)	does not flash

Purity	98%
Storage Temp.	2-8°C
UNSPSC	12352207

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