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Mitomycin C

ROCHE/10107409001 - crystalline powder, 98%, pkg of 2 mg

Synonym: Mitomycin C

CAS Number: 50-07-7
Empirical Formula (Hill Notation): C15H18N4O5
Molecular Weight: 334.33
Linear Formula: C15H18N4O5
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-10107409001 2 mg
$129.00
1/EA
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antibiotic activity spectrum Gram-negative bacteria
  Gram-positive bacteria
assay 98%
form crystalline powder
InChI 1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1
InChI key NWIBSHFKIJFRCO-WUDYKRTCSA-N
manufacturer/tradename Roche
mode of action DNA synthesis | interferes
mol wt 334.3
packaging pkg of 2 mg
Quality Level 100 
storage temp. 2-8°C
Application: Mitomycin C has been used:
•  to cease mitosis
• in phosphate buffer saline (PBS) for inactivation and plating mouse embryonic fibroblasts (MEFs)
• as mutagen in mutagenicity assay

Application: Mitomycin C is used as an inhibitor for studies of cell-free protein biosynthesis. It also inhibits DNA synthesis. It has been used as a genotoxic agent for tumor cells.
Biochem/physiol Actions: Mitomycin C (MMC) acts as a prototype for drugs with bioreductive alkylation. It is mainly found to be active under anaerobic conditions. MMC exhibits a vast clinical antitumor spectrum effectively in gastric, pancreatic and breast cancer.
General description: Mitomycin C is an antitumor antibiotic.
Other Notes: For life science research only. Not for use in diagnostic procedures.
Purity 98%
Storage Temp. 2-8°C
UNSPSC 12352207

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