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Aldehyde Dehydrogenase

ROCHE/10171832001 - from yeast

Synonym: Aldehyde dehydrogenase

Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-10171832001 250 units
 $310.00
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biological source yeast
form lyophilized
manufacturer/tradename Roche
optimum pH 8.75
packaging pkg of 250 U
Quality Level 100 
relevant disease(s) cancer
specific activity ~20 units/mg protein (At 25 °C with acetaldehyde as the substrate.)
storage temp. 2-8°C
Analysis Note: Contaminants: <0.01% “NADH oxidase”, ADH, and LDH each
Application: Aldehyde Dehydrogenase has been used to evaluate fiber-optic biosensors for measurement of acetaldehyde (AcH) in liquid phase (AcH biosensor).
Biochem/physiol Actions: Aldehyde dehydrogenase (ALDH) regulates the non-P450 aldehyde reduction enzyme system. It protects the cell from the effects of toxic aldehydes. Mutations in this gene are associated with Sjogren Larsson syndrome, Larsson syndrome, type II hyperprolinemia and cancer. ALDH takes part in the oxidation of aldehydes to acids. ALDH-2 lowers cardiac ischemia, which arises due to myocardial infarction or post cardiac surgery.
General description: Aldehyde dehydrogenase (ALDH) is a soluble enzyme and its activity depends on potassium ions and cysteine. The family of ALDH comprises of 19 genes in human. ALDH gene is expressed in the nucleus, cytosol, mitochondria and endoplasmic reticulum of the cell. ALDH is a component of nicotinamide adenine dinucleotide (NADH) and nicotinamide adenine dinucleotide phosphate (NADPH) recycling systems.
Other Notes: For life science research only. Not for use in diagnostic procedures.
Physical form: Enzyme is stabilized with potassium phosphate buffer, pH approximately 6.
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H332
Precautionary statements P261 - P271 - P304 + P340 + P312
RIDADR NONH for all modes of transport
WGK Germany WGK 2
Flash Point(F) does not flash
Flash Point(C) does not flash
activity specific activity: ~20 units/mg protein (At 25 °C with acetaldehyde as the substrate.)
Storage Temp. 2-8°C
Enzyme Commission (EC) Number 1.2.1.5   ( BRENDA  | IUBMB  )
UNSPSC 12352204

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