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n-Octylglucoside

ROCHE/10634425001 - non-ionic

Synonym: Octyl β-D-glucopyranoside; n-Octyl glucoside; OGP

CAS Number: 29836-26-8
Empirical Formula (Hill Notation): C14H28O6
Molecular Weight: 292.37
MDL Number: MFCD00063288
Linear Formula: C14H28O6
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-10634425001 10 g
$859.00
1/EA
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aggregation number 84
assay 99% (GC)
CMC 20-25 mM (20-25°C)
InChI 1S/C14H28O6/c1-2-3-4-5-6-7-8-19-14-13(18)12(17)11(16)10(9-15)20-14/h10-18H,2-9H2,1H3/t10-,11-,12+,13-,14-/m1/s1
InChI key HEGSGKPQLMEBJL-RKQHYHRCSA-N
manufacturer/tradename Roche
mol wt 292.4
  micellar avg mol wt 25,000
packaging pkg of 10 g
shipped in ambient
SMILES string CCCCCCCCO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
technique(s) dialysis: suitable
transition temp cloud point >100 °C
Application: N-Octylglucoside has been shown to increase the resolution of proteins in 2D gels. It is a mild and non-denaturing detergent for the solubilization and reconstitution of membrane proteins. N-Octylglucoside is easily removed by dialysis. N-Octylglucoside has been used in mass spectrometric immunoassay to homogenize MALDI (matrix assisted laser desorption/ionization) matrix draw and elution.
Application: Non-ionic, dialyzable detergent for the solubilization and isolation of membrane proteins. Has been shown to increase the resolution of proteins in 2D gels.
General description: 1-O-n-Octyl-β-D-glucopyranoside, octylglucoside, is a detergent with an octyl chain as hydrophobic residue and glucose as hydrophilic part. It is a non-ionic, dialyzable, mild and non-denaturing detergent which is used for the solubilization, isolation and reconstitution of membrane proteins.
Other Notes: For life science research only. Not for use in diagnostic procedures.
Preparation Note: Working concentration: 46 mM
Working solution: Solubility: > 50% (w/v) in double-dist. water, Tris-HCl 0.05 mol/l; pH7.4 or K-phosphate buffer 0.1 mol/l, pH 7.0 at 25 °C.
Storage conditions (working solution): Stability in Solution
A stock solution is stable at 2 to 8 °C for approx. 3 days. We would expect a long term stability of 6-12 months if stored frozen in portions at -15 to -25 °C, provided bacterial contamination is avoided.
Quality: Purity: 99% (from C), homogeneous (GC)

Ease of removal*: ++
CMC**: 14.5 mM at +25°C
Formula: C14H28O6
Storage and Stability: Store at 15 to 25 °C. (Store dry!)
RIDADR NONH for all modes of transport
WGK Germany WGK 1
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity 99% (GC)
UNSPSC 12352200

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