Histone H3
ROCHE/11034758001 - from calf thymus
Synonym: histone
Product Type: Chemical
| form | lyophilized |
| manufacturer/tradename | Roche |
| packaging | pkg of 1 mg |
| Quality Level | 100  |
| shipped in | wet ice |
| storage temp. | 2-8°C |
| Application: | Histone H3 has been used to determine the role of histones in metastasis. It has also been used in dot blot and western blotting. |
| Biochem/physiol Actions: | Histone proteins are basic building blocks of chromatin. Mutations in Histone H3 results in adult cerebellar high-grade gliomas. It controls protein-protein interactions to induce binding of trans-acting factors that “drive” chromatin condensation. H3.1 acts as a replication-dependent histone. |
| General description: | Lyophilizate. Mammals contain three main classes of histone H3 variants: the replicative histones (H3.1 and H3.2), the replacement histone (H3.3) and the centromeric histone (Cenp-A). Histone H3 is located on human chromosome 6p22. H3.1 is also called as HIST1H3E. It is mainly expressed in the S phase. |
| Other Notes: | For life science research only. Not for use in diagnostic procedures. |
| Preparation Note: | Working solution: Solvent is recommended in double-distilled water. |
| Quality: | Typical analysis: The preparation is electrophoretically homogeneous. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352204 |