dATP

ROCHE/11051440001 - =98%, solution, 100 mM, suitable for DNA sequencing, suitable for DNA amplification

Synonym: 2′-Deoxyadenosine 5′-triphosphate sodium salt solution; 2′-deoxy-adenosine-5′-triphosphate; deoxy-adenosine-5′-triphosphate, 2′-; dATP

Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-11051440001	250 µL	$96.90 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	98%
concentration	100 mM
description	Lithium salt
form	solution
InChI	1S/C10H16N5O12P3.Na/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(25-7)2-24-29(20,21)27-30(22,23)26-28(17,18)19;/h3-7,16H,1-2H2,(H,20,21)(H,22,23)(H2,11,12,13)(H2,17,18,19);/q;+1/p-1/t5-,6+,7+;/m0./s1
InChI key	YJWCICGGRLOGEH-VWZUFWLJSA-M
manufacturer/tradename	Roche
packaging	pkg of 250 μL (25 μmol; 100 mM)
Quality Level	100
SMILES string	[Na+].Nc1ncnc2n(cnc12)[C@H]3C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)O3
storage temp.	−20°C
technique(s)	DNA amplification: suitable
	DNA sequencing: suitable
	DNA synthesis: suitable
	PCR: suitable
usage	sufficient for 6,250 standard reactions (PCR)

Analysis Note:	Typical analysis: • ≤98% dATP (HPLC), ≤1.5% dADP (HPLC), ≤0.5% dAMP (HPLC) • Absorbance determination A₂₅₀/A₂₆₀, A₂₈₀/A₂₆₀, A₂₉₀/A₂₆₀ • DNase activity negative, according to the current Quality Control procedures • Suitability for PCR
Application:	2′-Deoxyadenosine 5′-triphosphate sodium salt solution is used in DNA sysnthesis reactions such as PCR, DNA sequencing and molecular cloning techniques.
Application:	dATP has been used to resume transcription.
Application:	Use dATP, lithium salt, for DNA sequencing, labeling, and all types of amplification reactions or primer-extension reactions.
Biochem/physiol Actions:	Deoxyadenosine-5-triphosphate (dATP) plays a major role in the initiation of apoptosis in vitro. dATP is considered as an inhibitor of mammalian ribonucleotide reductase, thereby DNA synthesis.
General description:	2′-Deoxyadenosine 5′-triphosphate (dATP) is made up of a nucleobase attached to deoxyribose and a 5’-hydroxyl on the sugar bound to a chain of three phosphate residues. dATP is used by cells for synthesis of DNA by DNA polymerases.
General description:	dATP is a 100 mM clear, colorless solution of the lithium salt (pH 7).Download the CofA, SDS and IFU s
Other Notes:	1 μmol dATP = 15.0 A₂₆₀ units
Other Notes:	For life science research only. Not for use in diagnostic procedures.
Other Notes:	Our PCR Grade deoxynucleotides are even purer than the lithium salts, to ensure excellent performance in your PCRs. PCR Grade deoxynucleotides contain the sodium salt of the nucleotide in PCR Grade Water. For your convenience, some of our deoxynucleotides are also available in: • nucleotide sets (all 4 nucleotides in separate vials) • ready-to-use nucleotide mixes (premixed solutions of all 4 nucleotides) They are also vital components of: • kits (dNTPs, buffer, and polymerase in separate vials) • ready-to-use mixes [polymerase, nucleotides, and buffer (premixed 2x solutions)]

RIDADR	NONH for all modes of transport
WGK Germany	nwg
Flash Point(F)	No data available
Flash Point(C)	No data available

Purity	98%
Storage Temp.	−20°C
UNSPSC	41116100

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