NAD
ROCHE/NAD98-RO - Grade II, free acid
Synonym: β-Nicotinamide adenine dinucleotide hydrate; β-DPN; β-NAD; Coenzyme 1; Cozymase; DPN; Diphosphopyridine nucleotide; NAD; Nadide
CAS Number: 53-84-9
Empirical Formula (Hill Notation): C21H27N7O14P2 · xH2O
Molecular Weight: 663.43 (anhydrous basis)
MDL Number: MFCD00036253
Linear Formula: C21H27N7O14P2 · xH2O
Product Type: Chemical
| λmax | 260 nm |
| assay | 98% (dry weight) |
| color | off-white |
| form | lyophilized |
| InChI | 1S/C21H27N7O14P2/c22-17-1 |
| InChI key | BAWFJGJZGIEFAR-NNYOXOHSSA |
| manufacturer/tradename | Roche |
| mol wt | Mr 663.4 |
| packaging | pkg of 1 g (10127981001) |
| pkg of 10 g (10621650001) | |
| pkg of 5 g (10127990001) | |
| pH | ~3.0 (50 mg/mL in water) |
| shipped in | wet ice |
| SMILES string | NC1=NC=NC2=C1N=CN2.O[C@@H |
| storage temp. | 2-8°C |
| Analysis Note: | Absorbance coefficients: 17.6 x 103 l x mol-1 x cm-1 at 260 nm, 5.9 x 103 l x mol-1 x cm-1 at 333 nm (CN complex) |
| Analysis Note: | ß-Nicotinamide adenine dinucleotide hydrate cofactor (NAD) has been used in an experimental protocol, done in order to mimic the citric acid cycle on an carbon electrode, in order to increase biofuel cell energy density. |
| Application: | NAD has been used in boiled-blood agar plate as a supplement for the growth of Actinobacillus pleuropneumoniae colony. |
| Biochem/physiol Actions: | Electron acceptor |
| Biochem/physiol Actions: | Nicotinamide adenine dinucleotide (NAD) acts as an electron carrier and significantly participates in enzyme-catalyzed oxido-reduction processes and many genetic processes. NAD cycles between the oxidized (NAD+) and reduced (NADH) forms to maintain a redox balance necessary for continued cell growth. This cofactor is also involved in microbial catabolism. β-NAD acts as a substrate for various enzymes in several cellular processes. |
| General description: | Nicotinamide adenine dinucleotide (NAD) is a cofactor containing an adenylic acid and a nicotinamide-5′-ribonucle |
| Other Notes: | For life science research only. Not for use in diagnostic procedures. |
| Other Notes: | This is the common form of NAD. |
| Packaging: | Packaged by solid weight. |
| Preparation Note: | Storage conditions (working solution): An aqueous solution in a concentration of 10 mg/ml (pH 2.5 to 3) maintains > 99% of its NAD content after 8 weeks of storage at 2 to 8 °C. The stability of an aqueous solution in a concentration of 40 mg/ml is not expected to differ from that of a solution in a concentration of 10 mg/ml. An aqueous solution in a concentration of 50 mg/ml (pH 2.0) maintains 97% of its NAD content after 2 days, 94% after 6 days and 91% after 10 days of storage at 2 to 8 °C and about 83% after 10 days of storage at 33 °C. An aqueous solution in a concentration of 1.38 mg/ml shows a decrease of NAD content of 4% after 8 weeks of storage at 2 to 8 °C, stored at -15 to -25 °C the stability is expected to be > 6 months. A solution of NAD in triethanolamine buffer (pH 5.0) maintians 90% of its NAD content after 10 days of storage at 2 to 8 °C and 80% after 10 days of storage at 33 °C. |
| Quality: | Absence of contaminants: LDH inhibitors are not detectable. Organic solvents: <0.5% (GC) |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 98% (dry weight) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |