NADPH

ROCHE/NADPH-RO - powder, =97% (dry weight)

Synonym: β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt hydrate; β-NADPH; 2′-NADPH hydrate; Coenzyme II reduced tetrasodium salt; Dihydronicotinamide adenine dinucleotide phosphate tetrasodium salt; NADPH Na₄; TPNH₂ Na₄; Triphosphopyridine nucleotide reduced tetrasodium salt

CAS Number: 2646-71-1 (anhydrous)
Empirical Formula (Hill Notation): C₂₁H₂₆N₇Na₄O₁₇P₃ · xH₂O
Molecular Weight: 833.35 (anhydrous basis)
MDL Number: MFCD00036263
Linear Formula: C₂₁H₂₆N₇Na₄O₁₇P₃ · xH₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-10107824001	100 mg	$262.00 1/EA	Add To Favorites
45-10621692001	500 mg	$1030.00 1/EA	Add To Favorites
45-10621706001	1 g	$1750.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

λ_max	260 and 340 nm
assay	97% (dry weight)
description	Tetrasodium salt
form	powder
InChI	1S/C21H30N7O17P3.4Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;;;/h1,3-4,7-8,10-11,13-16,20-21,29-31H,2,5-6H2,(H2,23,32)(H,36,37)(H,38,39)(H2,22,24,25)(H2,33,34,35);;;;/q;4*+1/p-4/t10-,11+,13-,14+,15-,16+,20-,21+;;;;/m0..../s1
InChI key	WYWWVJHQDVCHKF-MPUNMZHWSA-J
manufacturer/tradename	Roche
packaging	pkg of 1 g (10621706001)
	pkg of 100 mg (10107824001)
	pkg of 500 mg (10621692001)
Quality Level	100
shipped in	wet ice
SMILES string	[Na+].[Na+].[Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@H]2O[C@@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@H](OP([O-])([O-])=O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@H](O)[C@@H]2O
storage temp.	2-8°C

Analysis Note:	Absorbance coefficients: 15.0 x 10³ l x mol^-1 x cm^-1 at 260 nm, 6.3 x 10³ l x mol^-1 x cm^-1 at 340 nm
Application:	NADPH-RO has been used for the determination of thioredoxin reductase activity.
Biochem/physiol Actions:	NADPH is an electron donor and a cofactor for many redox enzymes including nitric oxide synthetase.
General description:	• Absorbance coefficients: 15.0 x 103 l x mol-1 x cm-1 at 260 nm, 6.3 x 103 l x mol-1 x cm-1 at 340 nm • Absorbance maxima: 260 nm and 340 nm • Molecular weight: NADPH-Na4: Mr = 833.4, NADPH: Mr = 745.4 • pH value in water: 8.0 ± 1.0 (10 mg/ml)
General description:	Amorphous powder bottled under nitrogen.
Other Notes:	For life science research only. Not for use in diagnostic procedures.
Other Notes:	Packaged based on solid weight.
Preparation Note:	Storage conditions (working solution): 2 to 8 °C 10 mg/ml in Na-bicarbonate buffer, pH 9, contains at least 95% NADPH after 4 weeks at 2 to 8 °C.
Quality:	• Purity: =97% ß-NADPH-Na4 based on dry weight (enzymatically and absorbance at 340 nm), =80% (absorbance at 260 nm) • Organic solvents: =3% (GC)

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	97% (dry weight)
Storage Temp.	2-8°C
UNSPSC	12352200

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