Synonym: Quercetin 3-D-galactoside; 3,3′,4′,5,7-Pentahydroxyflavone 3-D-galactoside; Hyperin; Hyperoside
CAS Number: 482-36-0
Empirical Formula (Hill Notation): C21H20O12
Molecular Weight: 464.38
EC Number: 207-580-6
MDL Number: MFCD00016933
Linear Formula: C21H20O12
Product Type: Chemical
| grade |
primary reference standard |
| InChI |
1S/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-27,29-30H,6H2/t13-,15+,17+,18-,21+/m1/s1 |
| InChI key |
OVSQVDMCBVZWGM-DTGCRPNFSA-N |
| manufacturer/tradename |
HWI |
| shelf life |
limited shelf life, expiry date on the label |
| SMILES string |
OC[C@H]1O[C@@H](OC2=C(Oc3cc(O)cc(O)c3C2=O)c4ccc(O)c(O)c4)[C@H](O)[C@@H](O)[C@H]1O |
| technique(s) |
gas chromatography (GC): suitable |
| |
HPLC: suitable |
| Application: |
The primary reference standard can be used for identification, assay, and purity testing, method development, and validation.
It can also be used as follows:
• Development of an ultra performance liquid chromatography-mass spectrometric method to determine hyperoside in rat plasma samples following sample treatment by protein precipitation and liquid-liquid extraction
• Multi-residue analysis of hyperoside, isoquercitrin, and eleutheroside E in botanical samples of Apocynum venetum L. and Eleutherococcus senticosus used in traditional Chinese medicine by HPLC combined with diode array detection (DAD)
• Ionic liquid vacuum microwave-assisted extraction (ILVMAE) of rutin, hyperoside, and hesperidin from Sorbus tianschanica leaf samples for their subsequent quantification by HPLC
• Simultaneous detection and quantification of vitexin, rutin, hyperoside, and quercetin in hawthorn flower and leaf extract samples using high-performance liquid chromatography combined with spectrophotometric detection (HPLC-UV)
|
| Biochem/physiol Actions: |
Protects against peroxide-induced oxidative damage to cells by scavenging reactive oxygen species and enhancing activity of anti-oxidant enzymes, in particular, catalase and glutathione peroxidase. |
| General description: |
Hyperoside is a flavonol glycoside compound used in Traditional Chinese medicine for its various beneficial effects, such as anti-inflammatory, anti-oxidant, anti-viral, and anti-cancer. |
| General description: |
Produced and qualified by HWI pharma services GmbH.
Exact content measured by quantitative NMR can be found on the certificate. |
| Other Notes: |
A flavonol glycoside widely distribute in plants, including mimosa and St. John′s wort. |
| Other Notes: |
This compound is commonly found in plants of the genus: crataegus eucalyptus hypericum sambucus |
| Symbol |
 GHS07 |
| Signal word |
Warning |
| Hazard statements |
H302 |
| Precautionary statements |
P264 - P270 - P301 + P312 - P501 |
| Hazard Codes |
Xn |
| Risk Statements |
22 |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
