Acetyl chloride
SIAL/00990 - puriss. p.a., ≥99.0% (T)
Synonym: Acetic acid chloride; Acetic chloride; Ethanoyl chloride
CAS Number: 75-36-5
Empirical Formula (Hill Notation): C2H3ClO
Molecular Weight: 78.50
EC Number: 200-865-6
MDL Number: MFCD00000719
Linear Formula: CH3COCl
Product Type: Chemical
| assay | ≥99.0% (T) |
| autoignition temp. | 1353 °F |
| bp | 52 °C (lit.) |
| cation traces | Al: ≤0.5 mg/kg |
| Ba: ≤0.1 mg/kg | |
| Bi: ≤0.1 mg/kg | |
| Ca: ≤0.5 mg/kg | |
| Cd: ≤0.05 mg/kg | |
| Co: ≤0.02 mg/kg | |
| Cr: ≤0.1 mg/kg | |
| Cu: ≤0.02 mg/kg | |
| Fe: ≤0.5 mg/kg | |
| K: ≤0.5 mg/kg | |
| Li: ≤0.1 mg/kg | |
| Mg: ≤0.1 mg/kg | |
| Mn: ≤0.02 mg/kg | |
| Mo: ≤0.1 mg/kg | |
| Na: ≤0.5 mg/kg | |
| Ni: ≤0.02 mg/kg | |
| Pb: ≤0.1 mg/kg | |
| Sr: ≤0.1 mg/kg | |
| Zn: ≤0.1 mg/kg | |
| density | 1.104 g/mL at 25 °C (lit.) |
| expl. lim. | 19 % |
| form | liquid |
| functional group | acyl chloride |
| grade | puriss. p.a. |
| InChI | 1S/C2H3ClO/c1-2(3)4/h1H3 |
| InChI key | WETWJCDKMRHUPV-UHFFFAOYSA |
| mp | −112 °C (lit.) |
| Quality Level | 200  |
| refractive index | n |
| n |
|
| SMILES string | CC(Cl)=O |
| vapor density | 2.7 (vs air) |
| vapor pressure | 11.69 psi ( 20 °C) |
| 32.33 psi ( 55 °C) |
| Application: | Acetyl chloride can be used as: • A degradation agent in the degradation of polyoxyethylene glycol monoalkyl ethers to determine the degree of ethoxylation using chromatography-mass spectrometry (MS). • A reagent with alcohols for the esterification of carboxylic acids, N-boc deprotection, and phosphoramide solvolysis reactions. |
| General description: | Acetyl chloride (acyl chloride) is an acetylation reagent used in esterification and Friedel-Crafts acylation reactions. |
| Symbol |   GHS02,GHS05 |
| Signal word | Danger |
| Hazard statements | H225 - H314 |
| Precautionary statements | P210 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P305 + P351 + P338 + P310 |
| Hazard Codes | F,C |
| Risk Statements | 11-14-34 |
| Safety Statements | 9-16-26-45 |
| RIDADR | UN 1717 8(3) / PGII |
| WGK Germany | WGK 1 |
| Flash Point(F) | 41.0 °F |
| Flash Point(C) | 5 °C |
| Supplemental Hazard Statements | EUH014 |
| Purity | ≥99.0% (T) |
| bp | 52 °C (lit.) |
| mp | −112 °C (lit.) |
| Density | 1.104 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12352100 |