Bergamottin
SIAL/01338 - analytical standard
Synonym: Bergamotine; Bergaptin
CAS Number: 7380-40-7
Empirical Formula (Hill Notation): C21H22O4
Molecular Weight: 338.40
MDL Number: MFCD00017409
Linear Formula: C21H22O4
Product Type: Chemical
| application(s) | food and beverages |
| assay | ≥98.0% (HPLC) |
| format | neat |
| grade | analytical standard |
| InChI | 1S/C21H22O4/c1-14(2)5-4-6 |
| InChI key | DBMJZOMNXBSRED-OQLLNIDSSA |
| mp | 75-80 °C |
| Quality Level | 100  |
| SMILES string | CC(C)=CCCC(C)=CCOc1c2 |
| storage temp. | 2-8°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Application: | Bergamottin may be used as an analytical standard to test its efficacy in the following: • Blocker of STAT3 activation pathway in tumor cells; its potential in the therapy of multiple myeloma (MM) and other cancers is investigated. • Prevention and the treatment of cancer via suppression of the NF-kB signaling pathway and its regulated gene products. |
| General description: | Bergamottin, a member of the furanocoumarin family, is primarily found in grapefruit juice. It is reported to be a novel signal transducer and activator of the transcription 3 (STAT3) inhibitor. It is a known drug inhibitor of cytochrome P450 34A and also exhibits diverse anti-tumor and anti-inflammatory activities. |
| Packaging: | Bottomless glass bottle. Contents are inside inserted fused cone. |
| Recommended products: | Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial . |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98.0% (HPLC) |
| mp | 75-80 °C |
| Storage Temp. | 2-8°C |
| UNSPSC | 85151701 |