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Chloroform

SIAL/02487 - analytical standard

Synonym: Methylidyne trichloride; Trichloromethane

CAS Number: 67-66-3
Empirical Formula (Hill Notation): CHCl3
Molecular Weight: 119.38
EC Number: 200-663-8
MDL Number: MFCD00000826
Linear Formula: CHCl3
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-02487-5ML 5 mL
$162.00
1/EA
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application(s) agriculture
cleaning products
cosmetics
environmental
food and beverages
personal care
assay ≥99.9% (GC)
bp 60.5-61.5 °C (lit.)
contains ~0.003% amylene as stabilizer
density 1.492 g/mL at 25 °C (lit.)
format neat
grade analytical standard
InChI 1S/CHCl3/c2-1(3)4/h1H
InChI key HEDRZPFGACZZDS-UHFFFAOYSA-N
mp −63 °C (lit.)
Quality Level 100 
refractive index n20/D 1.444-1.447
  n20/D 1.445 (lit.)
shelf life limited shelf life, expiry date on the label
SMILES string ClC(Cl)Cl
technique(s) gas chromatography (GC): suitable
  HPLC: suitable
vapor density 4.1 (vs air)
vapor pressure 160 mmHg ( 20 °C)
Application:

  • Chloroform for organic synthesis: Chloroform is widely used in organic synthesis, providing a reliable solvent for the creation and purification of chemical compounds. It facilitates various reactions, including the integration of lipid analysis using advanced chromatographic techniques (Panczel et al., 2024 ).

  • Chloroform as a catalyst in organic synthesis: Employed as a catalyst, chloroform enhances the catalytic efficiencies of various biochemical reactions, such as the activation methods in catalytic studies, aiding in the development of more efficient and sustainable chemical processes (Behera et al., 2024 ).

General description: Chloroform is a colorless, volatile, liquid derivative of trichloromethane with an ether-like odor. It is a commonly used laboratory solvent. Presently, it is used in the industry as a solvent and in the production of the refrigerant freon. It is majorly used in production of chlorodifluoromethane, which is a refrigerant and fluoropolymer feedstock. It degrades in air to produce phosgene, dichloromethane, formyl chloride, CO, CO2 and hydrogen chloride. It can be orally consumed or inhaled, as it can be quickly absorbed, metabolized and eliminated by mammals.
Recommended products: Find a digital Reference Material for this product available on our online platform ChemisTwin®  for NMR. You can use this digital equivalent on ChemisTwin®  for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here  and start your free trial .
Purity ≥99.9% (GC)
bp 60.5-61.5 °C (lit.)
mp −63 °C (lit.)
Density 1.492 g/mL at 25 °C (lit.)
Refractive Index n20/D 1.444-1.447; n20/D 1.445 (lit.)
UNSPSC 12191502

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