N-Ethyldiisopropylamine solution
SIAL/03439 - suitable for peptide synthesis, ~2 M in 1-methyl-2-pyrrolidinone
Synonym: N,N-
CAS Number: 7087-68-5
Empirical Formula (Hill Notation): C8H19N
Molecular Weight: 129.24
MDL Number: MFCD00008868
Linear Formula: C8H19N
Product Type: Chemical
application(s) | peptide synthesis |
concentration | ~2 M in 1-methyl-2-pyrrolidinone |
form | liquid |
impurities | ≤0.2% water (KFT) |
InChI | 1S/C8H19N/c1-6-9(7(2)3)8( |
InChI key | JGFZNNIVVJXRND-UHFFFAOYSA |
Quality Level | 100 |
refractive index | n |
SMILES string | CCN(C(C)C)C(C)C |
Application: | N,N-Diisopropylethylamine (DIPEA), also known as Hünig′s base, is a sterically hindered amine. It is commonly employed as a base in peptide synthesis. Additionally, DIPEA is also used in the Pd-catalyzed cross-coupling reactions, which include Heck coupling and Sonagashira coupling reactions. |
General description: | N-Ethyldiisopropylamine (EDIA) reacts with monoactivated Michael acceptors to afford symmetrical sulfones. |
Symbol | GHS02,GHS05,GHS06,GHS08 |
Signal word | Danger |
Hazard statements | H226 - H302 - H315 - H318 - H331 - H335 - H360FD |
Precautionary statements | P210 - P280 - P301 + P312 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313 |
Hazard Codes | T |
Risk Statements | 61-10-22-36/37/38-52/53 |
Safety Statements | 53-26-45-61 |
RIDADR | UN 2734PSN1 3(8) / PGII |
WGK Germany | WGK 2 |
Flash Point(F) | 73.4 °F |
Flash Point(C) | 23 °C |
Refractive Index | n |
UNSPSC | 12352100 |