1,2-Dibromoethane
SIAL/03505 - purum, ≥98.0% (GC)
Synonym: EDB; Ethylene dibromide
CAS Number: 106-93-4
Empirical Formula (Hill Notation): C2H4Br2
Molecular Weight: 187.86
EC Number: 203-444-5
MDL Number: MFCD00000233
Linear Formula: BrCH2CH2Br
Product Type: Chemical
| assay | ≥98.0% (GC) |
| bp | 131-132 °C (lit.) |
| density | 2.18 g/mL at 25 °C (lit.) |
| form | liquid |
| grade | purum |
| InChI | 1S/C2H4Br2/c3-1-2-4/h1-2H |
| InChI key | PAAZPARNPHGIKF-UHFFFAOYSA |
| mp | 8-11 °C (lit.) |
| Quality Level | 200  |
| refractive index | n |
| n |
|
| SMILES string | BrCCBr |
| vapor density | ~6.5 (vs air) |
| vapor pressure | 11.7 mmHg ( 25 °C) |
| Application: | 1,2-Dibromoethane can be used: • To generate vinyl bromide in situ, which can undergo a palladium-catalyzed cross-coupling reaction with aryl boronic acids to form functionalized styrene derivatives. • As a brominating agent of tertiary carbanions in sterically hindered molecules. • As a building block to synthesize 2-arylsulfonyl hydrazones, (±)-horsfiline and 7-oxo-2, 3-dihydro-7H-pyrido [1,2,3-de] [1,4] benzoxazine-6-carboxylic acids. |
| General description: | 1,2-Dibromoethane (EDB) is a water-soluble dihaloalkane that was widely used as a soil and grain fumigant. This led to the contamination of soil, surface, and groundwater with residual EDB. As it is a potent carcinogen and mutagen, many studies have been conducted to identify chemical reactions for its degradation in the environment. |
| Symbol |    GHS06,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H301 + H311 + H331 - H315 - H319 - H335 - H350 - H411 |
| Precautionary statements | P273 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338 |
| Hazard Codes | T,N |
| Risk Statements | 45-23/24/25-36/37/38-51/53 |
| Safety Statements | 53-45-61 |
| RIDADR | UN 1605 6.1 / PGI |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98.0% (GC) |
| bp | 131-132 °C (lit.) |
| mp | 8-11 °C (lit.) |
| Density | 2.18 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12352100 |