Dansyl chloride
SIAL/03641 - for HPLC derivatization, LiChropur™, ≥99.0% (HPLC)
Synonym: 5-
CAS Number: 605-65-2
Empirical Formula (Hill Notation): C12H12ClNO2S
Molecular Weight: 269.75
EC Number: 210-092-6
MDL Number: MFCD00003985
Linear Formula: C12H12ClNO2S
Product Type: Chemical
| assay | ≥99.0% (HPLC) |
| form | powder or crystals |
| grade | for HPLC derivatization |
| InChI | 1S/C12H12ClNO2S/c1-14(2)1 |
| InChI key | XPDXVDYUQZHFPV-UHFFFAOYSA |
| mp | 72-74 °C (lit.) |
| quality | LiChropur™ |
| Quality Level | 100  |
| SMILES string | CN(C)c1cccc2c(cccc12)S(Cl |
| solubility | acetone: 0.2 g/10 mL, clear to slightly turbid, yellow to very dark yellow-orange |
| storage temp. | 2-8°C |
| technique(s) | HPLC: suitable |
| Application: | A fluorogenic reagent for fluorescent N-terminal derivatization of amino acids and peptides and detection by reverse phase HPLC. |
| Application: | Dansyl chloride has been used for the fluorogenic labeling of xenoestrogens, 4-nonylphenol and bisphenol A prior to their determination by high-performance liquid chromatography (HPLC) with fluorescence detection. It has also been used for the derivatization of icariin in human serum samples after oral administration of Epimedium decoction, followed by its determination using ultrasensitive LC-tandem mass spectrometry (LC-MS) and for the derivatization of antitumoral agent ES-285 in dog plasma followed by its analysis by HPLC equipped with ultraviolet and fluorescence detection. |
| General description: | Dansyl chloride is a fluorogenic reagent which is typically employed for the derivatization of amino acids. |
| Legal Information: | LiChropur is a trademark of Merck KGaA, Darmstadt, Germany |
| Recommended products: | Discover LiChropur reagents ideal for HPLC or LC-MS analysis |
| Symbol |  GHS05 |
| Signal word | Danger |
| Hazard statements | H290 - H314 |
| Precautionary statements | P260 - P280 - P303 + P361 + P353 - P305 + P351 + P338 + P310 |
| Hazard Codes | C |
| Risk Statements | 34 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | UN 3261 8 / PGII |
| WGK Germany | WGK 3 |
| Purity | ≥99.0% (HPLC) |
| mp | 72-74 °C (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 41116105 |