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Dansyl chloride

SIAL/03641 - LiChropur, ≥99.0% (HPLC)

Synonym: 5-(Dimethylamino)naphthalene-1-sulfonyl chloride; DNSCl

CAS Number: 605-65-2
Empirical Formula (Hill Notation): C12H12ClNO2S
Molecular Weight: 269.75
EC Number: 210-092-6
MDL Number: MFCD00003985
Linear Formula: C12H12ClNO2S
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-03641-100MG 100 mg
$49.60
1/EA
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45-03641-10X100MG 100 mg
$360.00
1/EA
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assay ≥99.0% (HPLC)
form powder or crystals
grade derivatization grade ((HPLC))
InChI 1S/C12H12ClNO2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3
InChI key XPDXVDYUQZHFPV-UHFFFAOYSA-N
mp 72-74 °C (lit.)
quality LiChropur
Quality Level 100 
SMILES string CN(C)c1cccc2c(cccc12)S(Cl)(=O)=O
solubility acetone: 0.2 g/10 mL, clear to slightly turbid, yellow to very dark yellow-orange
storage temp. 2-8°C
technique(s) HPLC: suitable
Application: A fluorogenic reagent for fluorescent N-terminal derivatization of amino acids and peptides and detection by reverse phase HPLC.
Application: Dansyl chloride has been used for the fluorogenic labeling of xenoestrogens, 4-nonylphenol and bisphenol A prior to their determination by high-performance liquid chromatography (HPLC) with fluorescence detection. It has also been used for the derivatization of icariin in human serum samples after oral administration of Epimedium decoction, followed by its determination using ultrasensitive LC-tandem mass spectrometry (LC-MS) and for the derivatization of antitumoral agent ES-285 in dog plasma followed by its analysis by HPLC equipped with ultraviolet and fluorescence detection.
General description: Dansyl chloride is a fluorogenic reagent which is typically employed for the derivatization of amino acids.
Legal Information: LiChropur is a trademark of Merck KGaA, Darmstadt, Germany
Other Notes: Discover LiChropur reagents ideal for HPLC  or LC-MS  analysis
Purity ≥99.0% (HPLC)
mp 72-74 °C (lit.)
Storage Temp. 2-8°C
UNSPSC 41116105

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