Thiamine hydrochloride

SIAL/04573 - tested according to Ph. Eur.

Synonym: Thiamio hydrochloridum; Aneurine hydrochloride; Vitamin B₁ hydrochloride

CAS Number: 67-03-8
Empirical Formula (Hill Notation): C₁₂H₁₇ClN₄OS · HCl
Molecular Weight: 337.27
EC Number: 200-641-8
MDL Number: MFCD00012780
Linear Formula: C₁₂H₁₇ClN₄OS · HCl
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-04573-50G-F	50 g	$82.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

agency	tested according to Ph. Eur.
	USP/NF
assay	98.5-101.0% anhydrous basis
biological source	synthetic
form	solid
InChI	1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1
InChI key	DPJRMOMPQZCRJU-UHFFFAOYSA-M
mp	250 °C (dec.) (lit.)
Quality Level	200
SMILES string	CC1=NC(N)=C(C[N+]2=CSC(CCO)=C2C)C=N1.Cl.[Cl-]
solubility	alcohol: soluble 1 gm in 100 ml (95%)
	alcohol: soluble 1 gm in 315 ml (Absolute)
	benzene: insoluble
	chloroform: insoluble
	diethyl ether: insoluble
	glycerol: soluble 1 gm in 18 ml
	hexane: insoluble
	methanol: very soluble
	propylene glycol: soluble
	water: soluble 1 g/mL
storage temp.	2-8°C

Application:	Thiamine hydrochloride has been used as a keratin salts medium supplement for culturing log-phase fungus. It has also been used as a supplement of VB medium the minimal medium of Vogel and Bonner.
Biochem/physiol Actions:	Thiamine hydrochloride is a cheap, non-toxic and efficient catalyst for the synthesis of amidoalkyl naphthols. It inhibits the production of shikonin derivatives by suspension cultures of Lithospermum erythrorhizon. Additionally, thiamine hydrochloride addition to apple juice concentrates reduces its patulin content.
Biochem/physiol Actions:	Thiamine hydrochloride is a hydrochloride salt form of thiamine (Vitamin B₁). It is crucial for aerobic metabolism, cell growth, transmission of nerve impulses and acetylcholine synthesis.

Symbol	GHS07
Signal word	Warning
Hazard statements	H319
Precautionary statements	P264 - P280 - P305 + P351 + P338 - P337 + P313
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	98.5-101.0% anhydrous basis
mp	250 °C (dec.) (lit.)
Storage Temp.	2-8°C
UNSPSC	12352209

To Order From a Quote