Synonym: (+)-(S)-4,4′-Propylenedi-2,6-piperazinedione; (S)-(+)-1,2-Bis(3,5-dioxopiperazin-1-yl)propane; Cardioxane; ICRF-187; NSC169780; Zinecard
CAS Number: 24584-09-6
Empirical Formula (Hill Notation): C11H16N4O4
Molecular Weight: 268.27
MDL Number: MFCD00866449
Linear Formula: C11H16N4O4
Product Type: Chemical
application(s) |
clinical testing |
assay |
≥97.0% (GC) |
format |
neat |
grade |
analytical standard |
InChI |
1S/C11H16N4O4/c1-7(15-5-10(18)13-11(19)6-15)2-14-3-8(16)12-9(17)4-14/h7H,2-6H2,1H3,(H,12,16,17)(H,13,18,19)/t7-/m0/s1 |
InChI key |
BMKDZUISNHGIBY-ZETCQYMHSA-N |
Quality Level |
100 |
shelf life |
limited shelf life, expiry date on the label |
SMILES string |
C[C@@H](CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2 |
storage temp. |
2-8°C |
Biochem/physiol Actions: |
Dexrazoxane is a cardioprotective compound against anthracyclines. It functions by inhibiting topoisomerase II without inducing DNA strand breaks. Dexrazoxane is a + enantiomer of razoxane. |
Symbol |
GHS07 |
Signal word |
Warning |
Hazard statements |
H315 - H319 - H335 |
Precautionary statements |
P305 + P351 + P338 |
RIDADR |
NONH for all modes of transport |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥97.0% (GC) |
Storage Temp. |
2-8°C |
UNSPSC |
12352200 |