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Tamoxifen

SIAL/06734 - certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Synonym: (Z)-1-(p-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene; trans-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine

CAS Number: 10540-29-1
Empirical Formula (Hill Notation): C26H29NO
Molecular Weight: 371.51
EC Number: 234-118-0
MDL Number: MFCD00010454
Linear Formula: C6H5C(C2H5)=C(C6H5)C6H4OCH2CH2N(CH3)2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-06734-50MG 50 mg
 $125.00
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format neat
grade TraceCERT®
  certified reference material
InChI 1S/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25-
InChI key NKANXQFJJICGDU-QPLCGJKRSA-N
manufacturer/tradename Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
mp 97-98 °C (lit.)
product line TraceCERT®
Quality Level 300 
shelf life limited shelf life, expiry date on the label
SMILES string CCC(c1ccccc1)=C(/c2ccccc2)c3ccc(OCCN(C)C)cc3
storage condition under inert gas (Argon)
storage temp. 2-8°C
technique(s) gas chromatography (GC): suitable
Biochem/physiol Actions: Estrogen antagonist in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells. Protein kinase C inhibitor.
Biochem/physiol Actions: Protein kinase C inhibitor. Induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.
General description: This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com
Legal Information: TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany
mp 97-98 °C (lit.)
Storage Temp. 2-8°C
UNSPSC 41116107

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