Coenzyme Q₁₀

SIAL/07386 - analytical standard

Synonym: Q-10; Ubiquinone 50; Ubiquinone-10

CAS Number: 303-98-0
Empirical Formula (Hill Notation): C₅₉H₉₀O₄
Molecular Weight: 863.34
EC Number: 206-147-9
MDL Number: MFCD00042919
Linear Formula: C₅₉H₉₀O₄
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-07386-10MG	10 mg	$111.00 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

application(s)	cleaning products cosmetics food and beverages personal care
assay	≥97.5% (HPLC)
color	faint yellow to dark orange
form	powder
format	neat
grade	analytical standard
impurities	≤1.0% water
InChI	1S/C59H90O4/c1-44(2)24-15-25-45(3)26-16-27-46(4)28-17-29-47(5)30-18-31-48(6)32-19-33-49(7)34-20-35-50(8)36-21-37-51(9)38-22-39-52(10)40-23-41-53(11)42-43-55-54(12)56(60)58(62-13)59(63-14)57(55)61/h24,26,28,30,32,34,36,38,40,42H,15-23,25,27,29,31,33,35,37,39,41,43H2,1-14H3/b45-26+,46-28+,47-30+,48-32+,49-34+,50-36+,51-38+,52-40+,53-42+
InChI key	ACTIUHUUMQJHFO-UPTCCGCDSA-N
mp	49 °C
Quality Level	100
shelf life	limited shelf life, expiry date on the label
SMILES string	O=C(C(OC)=C1OC)C(C/C=C(C)/CC/C=C(CC/C=C(CC/C=C(CC/C=C(CC/C=C(CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CCC=C(C)C)C)C)C)C)C)=C(C)C1=O
storage temp.	−20°C

Application:	Coenzyme Q10 mitigates cadmium cardiotoxicity by downregulating NF-kB/NLRP3 inflammasome axis and attenuating oxidative stress in mice: Research demonstrates Coenzyme Q10′s effectiveness in reducing cardiac damage through antioxidant mechanisms and inflammation modulation, offering insights for potential human therapeutic applications (Antar et al., 2024 ). Adverse hematological profiles associated with chlorpromazine antipsychotic treatment in male rats: Preventive and reversal mechanisms of taurine and coenzyme-Q10: This study explores how Coenzyme Q10, along with taurine, can mitigate the negative hematological effects of chlorpromazine, suggesting its use in managing side effects in psychiatric treatments (Obukohwo et al., 2024 ). Nutritional Strategies for Muscle Atrophy: Current Evidence and Underlying Mechanisms: Discusses the role of Coenzyme Q10 in muscle health, particularly in preventing atrophy through mitochondrial support and enhancing cellular energy metabolism, pertinent for sports medicine and aging (Shen et al., 2024 ). Identification of a family of species-selective complex I inhibitors as potential anthelmintics: Although indirectly related, this study hints at the role of mitochondrial function, which could be linked to Coenzyme Q10′s effects in similar pathways, suggesting a novel application area in parasitology and infectious diseases (Davie et al., 2024 ).
Caution:	light sensitive
General description:	Coenzyme Q₁₀ is the central electron carrier in mitochondrial respiratory chain, originating from food intake as well as from endogenous synthesis. It commonly acts in its reduced form to prevent lipid peroxidation in biological membranes and in serum low-density lipoproteins (LDL). It also tends to protect the mitochondrial membrane proteins and DNA against oxidative damage along with lipid peroxidation.
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RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥97.5% (HPLC)
mp	49 °C
Storage Temp.	−20°C
UNSPSC	85151701

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