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(R)-(−)-3-Amino-1-Boc-piperidine

SIAL/07858 - ≥98.0% (TLC)

Synonym: (R)-1-Boc-3-piperidinamine; tert-Butyl (R)-3-amino-1-piperidinecarboxylate

CAS Number: 188111-79-7
Empirical Formula (Hill Notation): C10H20N2O2
Molecular Weight: 200.28
MDL Number: MFCD03094717
Linear Formula: C10H20N2O2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-07858-1G-F 1 g
 $283.00
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assay ≥98.0% (TLC)
InChI 1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-5-8(11)7-12/h8H,4-7,11H2,1-3H3/t8-/m1/s1
InChI key AKQXKEBCONUWCL-MRVPVSSYSA-N
optical activity [α]/D -28.5±2°, c = 1 in DMF
Quality Level 100 
SMILES string CC(C)(C)OC(=O)N1CCC[C@@H](N)C1
Application: (R)-3-Amino-1-Boc-piperidine can be used to prepare a benzoxazepine derivative named (R)-7-(3,5-dimethoxyphenyl)-N-(piperidin-3-yl)-4-propionyl-2,3,4,5-tetrahydro-1,4-benzoxazepine-9-carboxamide, a potent CBP/P300 bromodomain inhibitor.
General description: (R)-3-Amino-1-Boc-piperidine can be used as a precursor for the preparation of dipeptidyl peptidase IV inhibitors like linagliptin, alogliptin, and other antidiabetic agents.
Purity ≥98.0% (TLC)
UNSPSC 12352005

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