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1-Deoxynojirimycin

SIAL/08012 - analytical standard

Synonym: 1,5-Dideoxy-1,5-imino-D-sorbitol

CAS Number: 19130-96-2
Empirical Formula (Hill Notation): C6H13NO4
Molecular Weight: 163.17
MDL Number: MFCD00063474
Linear Formula: C6H13NO4
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-08012-10MG 10 mg
$623.00
1/EA
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assay ≥95.0% (HPLC)
format neat
grade analytical standard
InChI 1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1
InChI key LXBIFEVIBLOUGU-JGWLITMVSA-N
Quality Level 100 
shelf life limited shelf life, expiry date on the label
SMILES string OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O
Application: DNJ may be used as a reference standard for the determination of DNJ in: • Mulberry leaves by high-performance liquid chromatography (HPLC) equipped with evaporative light scattering detector (ELSD) as well as direct analysis in real-time (DART) ionization source coupled with triple quadrupole tandem mass spectrometry (MS/MS).
• Silkworms by hydrophilic interaction chromatography (HILIC) with MS/MS operating on multiple reaction monitoring (MRM) mode.
• Mulberry leaves of 132 varieties belonging to nine Morus species following its derivatization with fluorenylmethyl chloroformate (FMOC-Cl) by high-performance liquid chromatography (HPLC) combined with photodiode array (PDA) detector
• Development of an analytical method based on hydrophilic interaction chromatography (HILIC) coupled with tandem mass spectrometry (MS/MS) in positive ion electrospray ionization mode in the leaves of 32 cultivars of different Morus species
• HPLC method-based separation and quantification in the ethanol extracts of the leaves of Morus alba L. and Morus nigra with fluorimetric detection following pre-column derivatization with 9-fluorenylmethyl chloroformate
• 146 varieties of mulberry fruits from nine genera by HPLC in combination with UV-Vis dual-wavelength detection
• Human plasma by hybrid quadrupole/linear ion trap tandem mass spectrometry (QTRAP MS/MS).
General description: 1-Deoxynojirimycin is a polyhydroxypiperidine alkaloid and glucose analog, that has an -NH group substituting the O atom in the pyranose ring. It shows a significant α-glucosidase inhibitory effect in addition to antioxidant, antimicrobial, antidiabetic, antitumor, and anti-inflammatory behavior. It is commonly found in the roots of mulberry trees.

RIDADR NONH for all modes of transport
WGK Germany WGK 1
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95.0% (HPLC)
UNSPSC 85151701

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