3,4-Dihydroxybenzoic acid
SIAL/08992 - analytical standard
Synonym: Protocatechuic acid
CAS Number: 99-50-3
Empirical Formula (Hill Notation): C7H6O4
Molecular Weight: 154.12
EC Number: 202-760-0
MDL Number: MFCD00002509
Linear Formula: (HO)2C6H3CO2H
Product Type: Chemical
application(s) | cleaning products cosmetics flavors and fragrances food and beverages personal care |
assay | ≥97.0% (HPLC) |
format | neat |
grade | analytical standard |
InChI | 1S/C7H6O4/c8-5-2-1-4(7(10 |
InChI key | YQUVCSBJEUQKSH-UHFFFAOYSA |
mp | 197-200 °C (dec.) (lit.) |
Quality Level | 100 ![]() |
shelf life | limited shelf life, expiry date on the label |
SMILES string | OC(=O)c1ccc(O)c(O)c1 |
technique(s) | gas chromatography (GC): suitable |
HPLC: suitable |
Application: | 3,4-Dihydroxybenzoic acid may be used as a reference standard for the determination of: • Phenols in biomass pre-treatment hydrolysates by high-performance liquid chromatography method. • 3,4-Dihydroxybenzoic acid in wine by high-performance liquid chromatography with a microbore column. |
Biochem/physiol Actions: | Chemopreventive in several animal models of carcinogenesis. Blocks cell proliferation in the post-initiation phase. |
General description: | 3,4-Dihydroxybenzoic acid is a catabolite of epinephrine. It is a phenolic compound and an important constituent of lignin present in wine, green and black tea, and herbal medicines, which exhibits anti-inflammatory and antitumor promotion. 3,4-Dihydroxybenzoic acid is also a model matrix for ionization of peptides, proteins and carbohydrates in the MALDI (matrix-assisted laser desorption ionization mass spectroscopy) technique. |
Packaging: | Bottomless glass bottle. Contents are inside inserted fused cone. |
Symbol | ![]() |
Signal word | Warning |
Hazard statements | H315 - H319 - H335 |
Precautionary statements | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥97.0% (HPLC) |
mp | 197-200 °C (dec.) (lit.) |
UNSPSC | 85151701 |