8-Anilino-1-naphthalenesulfonic acid ammonium salt
SIAL/10416 - technical, ≥90% (NT)
Synonym: 1,8-ANS NH4; ANSA; Ammonium 8-
CAS Number: 28836-03-5
Empirical Formula (Hill Notation): C16H16N2O3S
Molecular Weight: 316.37
EC Number: 249-265-6
MDL Number: MFCD00012560
Linear Formula: C16H13NO3S · NH3
Product Type: Chemical
| assay | ≥90% (NT) |
| color | , Green to Dark Green and Grey to Dark Grey and Green-Grey |
| fluorescence | λex 388 nm; λem 470 nm in 0.1 M Tris, 0.2 M KCl, pH 9.0, BSA |
| form | powder |
| grade | technical |
| InChI | 1S/C16H13NO3S.H3N/c18-21( |
| InChI key | IPBNQYLKHUNLQE-UHFFFAOYSA |
| Quality Level | 200  |
| SMILES string | N.OS(=O)(=O)c1cccc2cccc(N |
| solubility | H2O: soluble |
| methanol: soluble | |
| NaOH: 1 N |
| Application: | ANS forms an inclusion complex with cyclodextrin. Such model systems are useful to mimic biological recognition and can be studied by measuring the change in fluorescence of free-ANS to complexed-ANS. When ANS enters the hydrophobic core of cyclodestrin, it’s fluorescence increases . Utilized in the reagent phase of a sodium-selective fiber-optic sensor. The reagent phase also contains a copper(II) polyelectrolyte, which binds to ANSA in the absence of sodium and quenches the fluorescence. In the presence of sodium, ANSA forms a cationic complex creating ion-pairs, causing it to fluoresce . ANS is often incorporated into di-block polymers and can be released by changes in the local environment (i.e., temperature, pH, etc.) . ANS is commonly used as a fluorescence probe to investigate molecular assemblies of surfactants and amphiphilic polymers because a blue shift of the emission maximum indicates the fluorophore is located in less polar media . Fluorescent probe for protein studies using methodologies such as steady-state and dynamic fluorescence measurements . |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥90% (NT) |
| UNSPSC | 12352106 |