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Potassium antimonyl tartrate trihydrate

SIAL/11126 - puriss., meets analytical specification of USP, 99.0-103.0%, powder

Synonym: Antimony potassium tartrate trihydrate; Tartar emetic

CAS Number: 28300-74-5
Empirical Formula (Hill Notation): C8H4K2O12Sb2 · 3H2O
Molecular Weight: 667.87
EC Number: 234-293-3
MDL Number: MFCD00167056
Linear Formula: C8H4K2O12Sb2 · 3H2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-11126-250G 250 g
 $137.00
1/EA		 Add To Favorites
45-11126-1KG 1 kg
 $312.00
1/EA		 Add To Favorites

 

assay 99.0-103.0%
cation traces As: ≤150 mg/kg
  Pb: ≤20 mg/kg
form powder
grade puriss.
impurities ≤0.02 mmol/g free acid
  ≤0.02 mmol/g free alkali
InChI 1S/2C4H4O6.2K.3H2O.2Sb/c2*5-1(3(7)8)2(6)4(9)10;;;;;;;/h2*1-2H,(H,7,8)(H,9,10);;;3*1H2;;/q2*-2;2*+1;;;;2*+3/p-4
InChI key WBTCZEPSIIFINA-UHFFFAOYSA-J
loss ≤2.7% loss on drying, 105 °C
mp ≥300 °C (lit.)
quality meets analytical specification of USP
Quality Level 200 
SMILES string O.O.O.[K+].[K+].O=C1O[Sb-]23OC1C4O[Sb-]5(OC(C(O2)C(=O)O3)C(=O)O5)OC4=O
Application: Potassium antimonyl tartrate trihydrate was employed as an Sb(III)-containing drug to investigate its ability to induce cell death associated with DNA fragmentation in axenic amastigotes of Leishmania infantum†
It may also be used as a standard solution to determine the metalloid concentration such as Sb(III) and Sb(V) in surface soil, using high performance liquid chromatography coupled to inductively coupled plasma-mass spectrometry (HPLC-ICP-MS).
General description: Potassium antimonyl tartrate trihydrate is a trivalent antimonial compound. It has been reported to be more toxic than pentavalent antimony (Pentostam) against Leishmania species. Its crystal structure has been investigated by the three-dimensional X-ray and white radiation neutron diffraction techniques. It crystallizes in space group C2221. Unit cell dimensions reported were: a = 11.192(2), b = 11.696(3), and c = 25.932(5)Å.
Purity 99.0-103.0%
mp ≥300 °C (lit.)
UNSPSC 12352100

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