2,4,6-Trimethylpyridine
SIAL/142387 - ReagentPlus®, 99%
Synonym: 2,4,6-Collidine; sym-Collidine
CAS Number: 108-75-8
Empirical Formula (Hill Notation): C8H11N
Molecular Weight: 121.18
EC Number: 203-613-3
MDL Number: MFCD00006338
Linear Formula: C8H11N
Product Type: Chemical
| assay | 99% |
| bp | 171-172 °C (lit.) |
| density | 0.917 g/mL at 25 °C (lit.) |
| form | liquid |
| InChI | 1S/C8H11N/c1-6-4-7(2)9-8( |
| InChI key | BWZVCCNYKMEVEX-UHFFFAOYSA |
| mp | −43 °C (lit.) |
| product line | ReagentPlus® |
| Quality Level | 200 ![]() |
| refractive index | n |
| SMILES string | Cc1cc(C)nc(C)c1 |
| Application: | 2,4,6-Trimethylpyridine (collidine, s-collidine, 2,4,6-collidine) has been used in the preparation of a library of N-acyl aminocoumarins bearing low-molecular-weight N-acyl groups. |
| Application: | Tissue fixative for electron microscopy. |
| Application: | Useful solvent for the cleavage of hindered esters by anhydrous lithium iodide. |
| General description: | 2,4,6-Trimethylpyridine is a pyridine derivative. It has a pK of 7.4. The product can react with trifluoroiodomethane in cyclopentane solution to afford 1:1 complex. This complex was investigated by NMR (Nuclear Magnetic Resonance) spectroscopy. Collidine-buffered osmium tetroxide solutions have been prepared by adding osmium tetroxide solution to it. These solutions have been used as fixative for electron microscopic studies. 2,4,6-Trimethylpyridine can undergo oxidation with potassium permanganate to form 2,4,6-pyridinetricarboxyl |
| General description: | Hindered base. |
| Legal Information: | ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Packaging: | 1 L in glass bottle |
| Packaging: | 5, 100, 500 mL in glass bottle |
| Symbol | ![]() GHS02,GHS06 |
| Signal word | Danger |
| Hazard statements | H226 - H302 + H332 - H311 - H315 - H319 - H335 |
| Precautionary statements | P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338 |
| Hazard Codes | Xn |
| Risk Statements | 10-20/21/22-36/37/38 |
| Safety Statements | 26-36/37 |
| RIDADR | UN 1992 6.1(3) / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | 131.0 °F - closed cup |
| Flash Point(C) | 55 °C - closed cup |
| Purity | 99% |
| bp | 171-172 °C (lit.) |
| mp | −43 °C (lit.) |
| Density | 0.917 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12352100 |



